MediGene AG: Notification § 27a

On 10 July 2015, QVT Financial LP informed us in accordance with Section 27a, para.1, sentence 1 and 3 German Securities Trading Act (Wertpapierhandelsgesetz - WpHG), that QVT Financial LP has exceeded a 10% holding threshold in Medigene AG.

QVT Financial LP confirmed the following:

1. The prevalent aim of the investment is realizing trading profits;

2. QVT Financial LP plans to acquire further voting rights of the Company within the next twelve months by means of a purchase or by other means;

3. QVT Financial LP does not intend to exert influence on the appointment or removal of members of the Company's administrative, managing and supervisory bodies; and

4. QVT Financial LP does not intend to achieve a material change in the Company's capital structure, in particular as regards the ratio between its own funds and external funds and the dividend policy.

In respect of the origin of the funds used to aquire the voting rights, QVT Financial LP notifies pursuant to Sec. 27a para. 1 sentence 4 WpHG that the acquisition of the voting rights is financed by 100% of own funds (Eigenmittel).

On 10 July 2015, QVT Financial GP LLC informed us in accordance with Section 27a, para.1, sentence 1 and 3 German Securities Trading Act (Wertpapierhandelsgesetz - WpHG), that has QVT Financial GP LLC exceeded a 10% holding threshold in Medigene AG.

QVT Financial GP LLC confirmed the following:

1. The prevalent aim of the investment is realizing trading profits;

2. QVT Financial GP LLC plans to acquire further voting rights of the Company within the next twelve months by means of a purchase or by other means;

3. QVT Financial GP LLC does not intend to exert influence on the appointment or removal of members of the Company's administrative, managing and supervisory bodies; and

4. QVT Financial GP LLC does not intend to achieve a material change in the Company's capital structure, in particular as regards the ratio between its own funds and external funds and the dividend policy.

In respect of the origin of the funds used to aquire the voting rights, QVT Financial GP LLC notifies pursuant to Sec. 27a para. 1 sentence 4 WpHG that the acquisition of the voting rights is financed by 100% of own funds (Eigenmittel).

On 10 July 2015, QVT Associates GP LLC informed us in accordance with Section 27a, para.1, sentence 1 and 3 German Securities Trading Act (Wertpapierhandelsgesetz - WpHG), that QVT Associates GP LLC has exceeded a 10% holding threshold in Medigene AG.

QVT Associates GP LLC confirmed the following:

1. The prevalent aim of the investment is realizing trading profits;

2. QVT Associates GP LLC plans to acquire further voting rights of the Company within the next twelve months by means of a purchase or by other means;

3. QVT Associates GP LLC does not intend to exert influence on the appointment or removal of members of the Company's administrative, managing and supervisory bodies; and

4. QVT Associates GP LLC does not intend to achieve a material change in the Company's capital structure, in particular as regards the ratio between its own funds and external funds and the dividend policy.

In respect of the origin of the funds used to aquire the voting rights, QVT Associates GP LLC notifies pursuant to Sec. 27a para. 1 sentence 4 WpHG that the acquisition of the voting rights is financed by 100% of own funds (Eigenmittel).

On 10 July 2015, QVT Fund V LP informed us in accordance with Section 27a, para.1, sentence 1 and 3 German Securities Trading Act (Wertpapierhandelsgesetz - WpHG), that has QVT Fund V LP exceeded a 10% holding threshold in Medigene AG.

QVT Fund V LP confirmed the following:

1.The prevalent aim of the investment is realizing trading profits;

2. QVT Fund V LP plans to acquire further voting rights of the Company within the next twelve months by means of a purchase or by other means;

3. QVT Fund V LP does not intend to exert influence on the appointment or removal of members of the Company's administrative, managing and supervisory bodies; and

4. QVT Fund V LP does not intend to achieve a material change in the Company's capital structure, in particular as regards the ratio between its own funds and external funds and the dividend policy.

In respect of the origin of the funds used to aquire the voting rights, QVT Fund V LP notifies pursuant to Sec. 27a para. 1 sentence 4 WpHG that the acquisition of the voting rights is financed by 100% of own funds (Eigenmittel).

On 10 July 2015, QVT Offshore Ltd. informed us in accordance with Section 27a, para.1, sentence 1 and 3 German Securities Trading Act (Wertpapierhandelsgesetz - WpHG), that has QVT Offshore Ltd. exceeded a 10% holding threshold in Medigene AG.

QVT Offshore Ltd. confirmed the following:

1. The prevalent aim of the investment is realizing trading profits;

2. QVT Offshore Ltd. plans to acquire further voting rights of the Company within the next twelve months by means of a purchase or by other means;

3. QVT Offshore Ltd. does not intend to exert influence on the appointment or removal of members of the Company's administrative, managing and supervisory bodies; and

4. QVT Offshore Ltd. does not intend to achieve a material change in the Company's capital structure, in particular as regards the ratio between its own funds and external funds and the dividend policy.

In respect of the origin of the funds used to aquire the voting rights, QVT Offshore Ltd. notifies pursuant to Sec. 27a para. 1 sentence 4 WpHG that the acquisition of the voting rights is financed by 100% of own funds (Eigenmittel).

On 10 July 2015, QVT Offshore II L.P. informed us in accordance with Section 27a, para.1, sentence 1 and 3 German Securities Trading Act (Wertpapierhandelsgesetz - WpHG), that has QVT Offshore II L.P. exceeded a 10% holding threshold in Medigene AG.

QVT Offshore II L.P. confirmed the following:

1. The prevalent aim of the investment is realizing trading profits;

2. QVT Offshore II L.P. plans to acquire further voting rights of the Company within the next twelve months by means of a purchase or by other means;

3. QVT Offshore II L.P. does not intend to exert influence on the appointment or removal of members of the Company's administrative, managing and supervisory bodies; and

4. QVT Offshore II L.P. does not intend to achieve a material change in the Company's capital structure, in particular as regards the ratio between its own funds and external funds and the dividend policy.

In respect of the origin of the funds used to aquire the voting rights, QVT Offshore II L.P. notifies pursuant to Sec. 27a para. 1 sentence 4 WpHG that the acquisition of the voting rights is financed by 100% of own funds (Eigenmittel).

The Executive Management Board

Planegg-Martinsried, 15 July 2015

Contact Medigene AG

Public & Investor Relations
Julia Hofmann / Anja Clausnitzer
Email: investor@medigene.com
Tel.: +49 - (0)89 - 20 00 33 33 01

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