PLEASANTON, CA--(Marketwire - December 03, 2009) -
C3-Jian, Inc. and Matrix Sensors, Inc. have
announced a collaboration in which engineered peptides from C3-Jian will be
used on Matrix Sensors' microchip molecular detector arrays, allowing
initial evaluation of a diagnostic assay platform for commercial use.
The use of engineered peptides can act as replacements for antibodies in
antibody-panel type assays for specific biomarkers and provides several
advantages, including efficiency in production, cost, reliability and
robustness. In addition, a peptide array can alert to the presence of an
unknown pathogen and provide a first step towards identification. Matrix
Sensors' technology provides an array of mass-sensitive detectors allowing
direct detection of reacting molecules without the complexities typically
associated with label-based systems. This provides a path to a simple,
"dipstick" based diagnostic assay using a Matrix microchip and a C3-Jian
The combination of these diagnostics and species-specific targeting of
antimicrobials, another C3-Jian technology, represents an opportunity for
focused treatment. This approach represents a significant improvement
beyond today's current practice of using broad-spectrum antibiotics for
bacterial infections, contributing to the emergence of drug-resistant
strains. The ultra high analyte resolution and accuracy of the Matrix
sensors allows attogram (one quintillionth of a gram) resolution of
specific molecules, and is extremely well suited to the application of
"We are extremely excited by the focus of the joint collaboration," said
Wenyuan Shi, Ph.D., Chief Scientific Advisor at C3-Jian, and Professor of
Microbiology at the UCLA School of Medicine. "These efforts will allow us
to further develop selective, efficacious and safer treatment modalities
for infectious diseases with easier to use, lower cost, ultra-sensitive,
rapid pathogen detection."
About C3-Jian, Inc.
Founded in 2005, C3-Jian, Inc. ("C3") is a clinical-stage biotechnology
company based in Los Angeles, California. The company is developing novel
products to diagnose, treat and prevent human, animal and plant diseases.
The lead compounds are focused on bacterial and fungal infections,
especially those occurring on mucosal surfaces and in industrial biofilms.
About Matrix Sensors, Inc.
Matrix Sensors, Inc. provides innovative technologies in the areas of life
science bio-molecule and gas sensing measurements. Founded in March 2006,
Matrix Sensors' technology promises to be the first electronic microchip
product featuring both ultra high analyte resolution and accuracy. The
technology achieves attogram resolution of specific molecules of interest.