BioSpace.com

Biotech and Pharmaceutical
News & Jobs
Search the Site
 
   
Biotechnology and Pharmaceutical Channel Medical Device and Diagnostics Channel Clinical Research Channel BioSpace Collaborative    Job Seekers:  Register | Login          Employers:  Register | Login  

NEWSLETTERS
Free Newsletters
Archive
My Subscriptions

NEWS
News by Subject
News by Disease
News by Date
PLoS
Search News
Post Your News
JoVE

CAREER NETWORK
Job Seeker Login
Most Recent Jobs
Browse Biotech Jobs
Search Jobs
Post Resume
Career Fairs
Career Resources
For Employers

HOTBEDS
Regional News
US & Canada
  Biotech Bay
  Biotech Beach
  Genetown
  Pharm Country
  BioCapital
  BioMidwest
  Bio NC
  BioForest
  Southern Pharm
  BioCanada East
  US Device
Europe
Asia

DIVERSITY

INVESTOR
Market Summary
News
IPOs

PROFILES
Company Profiles

START UPS
Companies
Events

INTELLIGENCE
Research Store

INDUSTRY EVENTS
Biotech Events
Post an Event
RESOURCES
Real Estate
Business Opportunities

 News | News By Subject | News by Disease News By Date | Search News
eNewsletter Signup
Miles
Km80.5

   

Lundbeck Inc. (LUN.CO) and Otsuka Pharmaceutical Co., Ltd. Release: Phase II Clinical Data Show Statistically Sgnificant Improvement for Lu AE58054 as Addon to Donepezil, Versus donepezil Alone, on Cognitive Symptoms of Alzheimer's Disease


7/17/2013 7:26:22 AM

Staying up-to-date has never been simpler. Sign up for the free GenePool newsletter today!

Valby, Copenhagen, 2013-07-16 20:28 CEST (GLOBE NEWSWIRE) -- Phase II clinical data show statistically significant improvement for Lu AE58054 as add-on to donepezil, versus donepezil alone, on cognitive symptoms of Alzheimer's diseasei

Lundbeck and Otsuka present data at Alzheimer's Association International Conference 2013

Lu AE58054 is a selective 5-HT6 receptor antagonist under investigation for the treatment of Alzheimer's diseaseii

Lundbeck and Otsuka will initiate a phase III clinical program in about 3,000 patients during the second half of 2013

The two companies' focus on the 5-HT6 receptor is a different approach from the amyloid and tau hypotheses that have underpinned much of the research to date on Alzheimer's diseaseiii

36 million people worldwide are estimated to have dementia, with the number expected to almost double every 20 yearsiv,v

Valby, Denmark and Tokyo, Japan, 16 July 2013 - H. Lundbeck A/S (Lundbeck) and Otsuka Pharmaceutical Co., Ltd. (Otsuka) today announced the presentation of the first clinical data on the investigational drug Lu AE58054 in Alzheimer's disease at the Alzheimer's Association International Conference 2013 (AAIC 2013) in Boston.

The phase II clinical study demonstrated that treatment with Lu AE58054 as add-on to donepezil for six months improved cognitive performance in patients with moderate Alzheimer's diseasei.

"I am very pleased with the data achieved in this project. Lu AE58054 potentially represents a new approach to Alzheimer's disease and a continuation of Lundbeck's commitment to addressing this complicated disease", says Executive Vice President Anders Gersel Pedersen, Head of Research & Development at Lundbeck. "It is my hope that the clinical phase III program will confirm results seen from this phase II trial, and demonstrate a positive outcome on this devastating disease".

William H. Carson, M.D., President and Chief Executive Officer, Otsuka Pharmaceutical Development and Commercialization, Inc., notes that "Our investigation of the 5-HT6 receptor and its role in memory processes and in Alzheimer's disease is encouraging. We are eager to continue phase III trials with Lundbeck".

Read more: Phase II clinical data show statistically significant improvement for Lu AE58054 as addon to donepezil, versus donepezil alone, on cognitive symptoms of Alzheimer's diseasei - FierceBiotech http://www.fiercebiotech.com/press-releases/phase-ii-clinical-data-show-statistically-significant-improvement-lu-ae5805-0#ixzz2ZJEF0vM0 Subscribe at FierceBiotech

Help employers find you! Check out all the jobs and post your resume.


Read at BioSpace.com

   

ADD TO DEL.ICIO.US    ADD TO DIGG    ADD TO FURL    ADD TO STUMBLEUPON    ADD TO TECHNORATI FAVORITES