Low Vitamin B12 May Speed Brain Shrinkage, Rush University Medical Center Study

Older people with low levels of vitamin B12 may be more prone to age-related memory declines and brain shrinkage. That finding, reported in Neurology, comes from researchers at Chicago's Rush University Medical Center. They found that older people with blood markers associated with vitamin B12 deficiency had the smallest brains and the lowest scores on tests measuring thinking, reasoning, and memory. The brain naturally shrinks as people age, and it appears that those with the greatest reductions in brain volume are most at risk for Alzheimer's disease and other age-related dementias.

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