Lonza Group Expands Single-Use Manufacturing Capacity In Slough (UK) Facility To Meet Customer Demand

• Lonza adds two 1000L single-use bioreactor systems to its current mammalian manufacturing capacity

• The additional bioreactors will help meet the increasing demand for flexible manufacturing capacity for clinical development supply

Basel, Switzerland, 13 January 2016 – Lonza, a global leader in biological manufacturing, today announced the expansion of mammalian production capacity at its Slough (UK) facility. Based on the increased demand for biopharmaceutical development and clinical manufacturing services, two 1000L single-use bioreactors will be installed at the site. This expansion will significantly increase the existing single-use manufacturing capacity in Slough while allowing current operations to continue without interruption. The additional mammalian manufacturing capacity is now available to customers.

Lonza’s cGMP facility in Slough is the center of excellence for development and clinical supply. The site provides cell line construction, process development and clinical manufacturing services for mammalian-derived biotherapeutics.

The increase in bioreactor capacity continues the implementation of single-use technologies at the Slough site and complements existing single-use equipment for both seed train systems and downstream processing, including chromatography, filtration and ultrafiltration unit operations. The new reactors are equipped with controllers that enable parallel reactor operations, expanded process capabilities with flexible operating scales and bioreactor types. Use of these technologies supports Lonza’s ability to accommodate a variety of customer projects and processes across scales and clinical phases.

“The ease of installation, commissioning and validation of single-use bioreactors allows us to meet the increased market demand for clinical manufacturing,” said Michael Brown, Head of Operations for Clinical Development, Lonza Pharma&Biotech.

For more information on the Slough site and its capabilities, visit www.lonza.com/oursites.

About Lonza

Lonza is one of the world’s leading and most-trusted suppliers to the pharmaceutical, biotech and specialty ingredients markets. We harness science and technology to create products that support safer and healthier living and that enhance the overall quality of life.

Not only are we a custom manufacturer and developer, Lonza also offers services and products ranging from active pharmaceutical ingredients and stem-cell therapies to drinking water sanitizers, from the vitamin B compounds and organic personal care ingredients to agricultural products, and from industrial preservatives to microbial control solutions that combat dangerous viruses, bacteria and other pathogens.

Founded in 1897 in the Swiss Alps, Lonza today is a well-respected global company with more than 40 major manufacturing and R&D facilities and approximately 9,800 employees worldwide. The company generated sales of about CHF 3.64 billion in 2014 and is organized into two market-focused segments: Pharma&Biotech and Specialty Ingredients. Lonza’s stock is publicly traded on the Swiss and the Singapore stock exchanges. Further information can be found at www.lonza.com.

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