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Liquid Crystal Droplets Could Replace Horseshoe Crab Blood In Common Endotoxin Test, University of Wisconsin-Madison Study



5/24/2011 7:56:41 AM

The Food and Drug Administration requires every drug they certify to be tested for certain poisons that damage patient health. The current gold standard for this is the limulus amoebocyte lysate (LAL) assay that involves using the blood of horseshoe crabs, which strangely enough is blue, to test for endotoxin, a substance commonly associated with many symptoms caused by bacterial infections. But researchers at the Department of Chemical and Biological Engineering at the University of Wisconsin-Madison have found what may be a more effective way to test for endotoxin that involves liquid crystals, the same material used to make some flat screen computer monitors and televisions.



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