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Kidney Disease May be Written on Your Face, King's College London Study



4/26/2013 8:15:53 AM

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People with a certain kind of kidney disease have characteristic facial features that may reflect the genetic mutation they carry. Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common genetic kidney disorder. In the UK, it accounts for around 1 in 10 people on dialysis and 1 in 8 of those with a kidney transplant. About 64-85 percent of ADPKD families have mutations in the PKD1 gene and about 15-36 percent have mutations in the related PKD2 gene.

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