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Key Brain Signaling Mechanism For Rapidly Acting Antidepressants, Yale University Study


11/20/2013 6:28:14 AM

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Two years ago, mammalian target of rapamycin or mTOR, a signaling protein, was identified as a key mediator of the antidepressant effects of ketamine, the first rapidly acting antidepressant medication to be identified. Several years later, a group at the National Institutes of Mental Health Intramural Program reported that scopolamine, a muscarinic acetylcholine receptor antagonist, also produced rapidly appearing antidepressant effects, similar to the actions of ketamine.

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Read at ScienceDaily


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