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Johns Hopkins Kimmel Cancer Center and Children's Hospital of Philadelphia Scientists Find "Bully" Genes in Common Childhood Tumor



12/3/2012 7:57:29 AM

In a genome sequencing study of 74 neuroblastoma tumors in children, scientists at the Johns Hopkins Kimmel Cancer Center and the Children's Hospital of Philadelphia (CHOP) found that patients with changes in two genes, ARID1A and ARID1B, survive only a quarter as long as patients without the changes. The discovery could eventually lead to early identification of patients with aggressive neuroblastomas who may need additional treatments.

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