BioSpace.com

Biotech and Pharmaceutical
News & Jobs
Search the Site
 
   
Biotechnology and Pharmaceutical Channel Medical Device and Diagnostics Channel Clinical Research Channel BioSpace Collaborative    Job Seekers:  Register | Login          Employers:  Register | Login  

NEWSLETTERS
Free Newsletters
Archive
My Subscriptions

NEWS
News by Subject
News by Disease
News by Date
PLoS
Search News
Post Your News
JoVE

CAREER NETWORK
Job Seeker Login
Most Recent Jobs
Browse Biotech Jobs
Search Jobs
Post Resume
Career Fairs
Career Resources
For Employers

HOTBEDS
Regional News
US & Canada
  Biotech Bay
  Biotech Beach
  Genetown
  Pharm Country
  BioCapital
  BioMidwest
  Bio NC
  BioForest
  Southern Pharm
  BioCanada East
  US Device
Europe
Asia

DIVERSITY

INVESTOR
Market Summary
News
IPOs

PROFILES
Company Profiles

START UPS
Companies
Events

INTELLIGENCE
Research Store

INDUSTRY EVENTS
Biotech Events
Post an Event
RESOURCES
Real Estate
Business Opportunities

 News | News By Subject | News by Disease News By Date | Search News
eNewsletter Signup
Miles
Km80.5

   

iZumi Bio Recruits Leading iPS Scientist, John Dimos, to Translate Stem Cell Breakthrough Into Patient Benefits


8/7/2008 9:01:42 AM

MOUNTAIN VIEW, Calif., Aug. 6 /PRNewswire/ -- iZumi Bio, Inc., announced today that John T. Dimos, Ph.D., first author of the landmark Science paper "Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons," will join its team of scientists translating induced pluripotent stem (iPS) cell research into patient benefits. Dimos' work demonstrates the potential for iPS-derived cells in regenerative medicine.

(Logo: http://www.newscom.com/cgi-bin/prnh/20080806/AQW065LOGO)

iPS cells are "reprogrammed" adult cells that have similar applications and potential to those of human embryonic stem (ES) cells, yet do not raise the same ethical concerns and can be generated in a patient-specific manner to maintain the disease-causing genetic profile while avoiding immune rejection.

Dimos' Science publication (online 31 July 2008; 10.1126/science.1158799) demonstrates that iPS cells derived from an individual patient can be differentiated into motor neurons, the cell type affected in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. Large-scale, standardized production of such iPS-derived cells could be used for a variety of applications including models for drug discovery and cell-based therapies. Dimos conducted his work as a postdoctoral fellow in Kevin Eggan's lab at the Harvard Stem Cell Institute (http://www.hsci.harvard.edu). He earned his Ph.D. in Molecular Biology at Princeton University in Ihor Lemischka's laboratory, where he studied what defines a stem cell at the gene expression level.

"We are delighted that John has chosen iZumi to develop his groundbreaking research into practical regenerative medicine applications," said Thane Kreiner, Ph.D., President and CEO of iZumi. "We are committed to working with the most talented scientists worldwide to ensure that the enabling iPS technology benefits patients."

"There is broad interest in translating this basic research into discovery paradigms aimed at patient benefits," said Dimos. "iZumi has all the elements in place to successfully lead this translation including first-class investors, scientific leaders and collaborators; an experienced management team; and a passion for improving human health. I am honored to join the team."

About iZumi

iZumi Bio, Inc. was founded in 2007 and is funded by Kleiner Perkins Caufield and Byers and Highland Capital Partners. iZumi is using the power of induced pluripotent stem cells (iPS) to transform drug discovery and regenerative medicine. In June, 2008, iZumi announced a broad regenerative medicine and cardiovascular disease partnership with The Gladstone Institutes. The name iZumi, which means "fountain of youth," was chosen to honor the Japanese origins of iPS technology. iZumi is located in Mountain View, California.



CONTACT: Carin Ganz, +1-312-596-3411, Carin.Ganz@bm.com, for iZumi Bio,
Inc.



Read at BioSpace.com

iZumi Bio
 
 

ADD TO DEL.ICIO.US    ADD TO DIGG    ADD TO FURL    ADD TO STUMBLEUPON    ADD TO TECHNORATI FAVORITES