BioSpace.com

Biotech and Pharmaceutical
News & Jobs
Search the Site
 
   
Biotechnology and Pharmaceutical Channel Medical Device and Diagnostics Channel Clinical Research Channel BioSpace Collaborative    Job Seekers:  Register | Login          Employers:  Register | Login  

NEWSLETTERS
Free Newsletters
Archive
My Subscriptions

NEWS
News by Subject
News by Disease
News by Date
PLoS
Search News
Post Your News
JoVE

CAREER NETWORK
Job Seeker Login
Most Recent Jobs
Browse Biotech Jobs
Search Jobs
Post Resume
Career Fairs
Career Resources
For Employers

HOTBEDS
Regional News
US & Canada
  Biotech Bay
  Biotech Beach
  Genetown
  Pharm Country
  BioCapital
  BioMidwest
  Bio NC
  BioForest
  Southern Pharm
  BioCanada East
  US Device
Europe
Asia

DIVERSITY

INVESTOR
Market Summary
News
IPOs

PROFILES
Company Profiles

START UPS
Companies
Events

INTELLIGENCE
Research Store

INDUSTRY EVENTS
Biotech Events
Post an Event
RESOURCES
Real Estate
Business Opportunities

 News | News By Subject | News by Disease News By Date | Search News
eNewsletter Signup
Miles
Km80.5

   

Integrated DNA Technologies Release: Discussing the Science of Big DNA


9/24/2013 9:00:10 AM

free biotech news Get the latest biotech news where you want it. Sign up for the free GenePool newsletter today!

CORALVILLE, IA – 23 September 2013 – In the latest issue of DECODED, the quarterly newsletter from Integrated DNA Technologies (IDT), Dr Dan Gibson discusses the science of big DNA. Dr Gibson spent most of the last decade working at the J Craig Venter Institute, as well as Synthetic Genomics Inc. (SGI), to develop, establish, and commercialize methods to take synthetic biology beyond its current limitations. In 2010 Dr Gibson and his team produced a DNA construct of 1.1 Mb, the largest synthetic DNA sequence to date, something which had not been achievable using traditional restriction/ligation methodologies. Instead, the team developed the Gibson Assembly™ Method, which uses a unique enzyme mix to assemble DNA elements with 20–80 overlapping bases. Once reamplified, the population, enriched with the correct sequence, is much faster to screen. The technology makes possible the creation of 10–30 kb sequences—the size of an entire biological pathway—in less than a week, and without cloning into E. coli. Dr Gibson and his team are currently looking at ways in which they can refine DNA assembly methods; improve large gene delivery to host cells; and develop methods that rely less on host organisms for copying their synthetic constructs.

Read the full article ‘Synthetic Life: Dr Dan Gibson Discusses the Science of Big DNA’ in the latest issue of DECODED. For more information please visit www.idtdna.com. Follow us on twitter @idtdna for real-time updates and insights.

About IDT

Integrated DNA Technologies (IDT) is the largest supplier of custom nucleic acids in the world, serving academic, government, and commercial researchers in biotechnology, clinical diagnostics, and pharmaceutical development. IDT's primary business is the manufacture of custom, synthetic DNA and RNA oligonucleotides. Today, IDT synthesizes and ships an average of 36,000 custom oligos per day to more than 86,000 customers worldwide. IDT manufacturing locations include facilities in Coralville, Iowa; San Diego, Calif.; Leuven, Belgium; and Singapore. For more information visit www.idtdna.com.

Integrated DNA Technologies

800-328-2661 (US & Canada)

+1 319-626-8400 (outside US)

productinfo@idtdna.com

www.idtdna.com

Help employers find you! Check out all the jobs and post your resume.


Read at BioSpace.com

   

ADD TO DEL.ICIO.US    ADD TO DIGG    ADD TO FURL    ADD TO STUMBLEUPON    ADD TO TECHNORATI FAVORITES