Inhibition of Cell Migration by Gene Silencing - Measured with the xCELLigence Cell Analysis System from Roche

PENZBERG, Germany--(BUSINESS WIRE)--Cell migration is an important process in the development of organisms, as well as during immune surveillance and wound healing. For cancer development, the potential of cells to migrate or to grow invasively is, in addition to proliferation, the most important disease-causing factor. The inhibition of cell migration is a key target of the new anti-inflammatory therapies. In a recent study, Markus Greiner and Richard Zimmermann (Saarland University, Homburg/Saar, Germany) used the RTCA DP Instrument with the CIM-Plate 16 of Roche Applied Science (SWX:RO) (SWX:ROG) (Pink Sheets: RHHBY) to evaluate the influence of a cellular protein on the migration potential of a wide range of tumor entities represented by diverse cell lines. Their results show evidence that this protein is involved in the general migration pathway in all cancers examined, providing a possible new therapeutic target. These findings are the starting point for further investigations to understand the cellular processes involved in migration at the molecular level.