Indiana University School of Medicine Scientists Find Potential New Clues for Identifying Breast Cancer Risk

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New research provides critical insights into how normal breast precursor cells may be genetically vulnerable to develop into cancer. The research is published June 4th in the inaugural issue of Stem Cell Reports, an open-access journal from the International Society of Stem Cell Research (ISSCR) published by Cell Press. Scientists discovered that a particular class of normal breast precursor cells have extremely short chromosome ends (known as telomeres). As a result, these cells would be expected to be prone to acquiring mutations that lead to cancer if they managed to stay alive. These findings suggest new indicators for identifying women at higher risk for breast cancer and provide insights into potential new strategies to detect, treat, and prevent the disease.

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