BioSpace.com

Biotech and Pharmaceutical
News & Jobs
Search the Site
 
   
Biotechnology and Pharmaceutical Channel Medical Device and Diagnostics Channel Clinical Research Channel BioSpace Collaborative    Job Seekers:  Register | Login          Employers:  Register | Login  

NEWSLETTERS
Free Newsletters
Archive
My Subscriptions

NEWS
News by Subject
News by Disease
News by Date
PLoS
Search News
Post Your News
JoVE

CAREER NETWORK
Job Seeker Login
Most Recent Jobs
Browse Biotech Jobs
Search Jobs
Post Resume
Career Fairs
Career Resources
For Employers

HOTBEDS
Regional News
US & Canada
  Biotech Bay
  Biotech Beach
  Genetown
  Pharm Country
  BioCapital
  BioMidwest
  Bio NC
  BioForest
  Southern Pharm
  BioCanada East
  US Device
Europe
Asia

DIVERSITY

INVESTOR
Market Summary
News
IPOs

PROFILES
Company Profiles

START UPS
Companies
Events

INTELLIGENCE
Research Store

INDUSTRY EVENTS
Biotech Events
Post an Event
RESOURCES
Real Estate
Business Opportunities

 News | News By Subject | News by Disease News By Date | Search News
eNewsletter Signup
Miles
Km80.5

   

ImmuPharma plc (IMM.L) - Update on Progress of Phase I/IIa Clinical Trial


2/22/2011 10:52:55 AM

February, 2011 -- ImmuPharma plc (LSE:IMM) (“Immupharma” or the “Company” or the “Group”), the specialist discovery and development pharmaceutical company is pleased to announce encouraging results from its ongoing phase I/IIa clinical trial in cancer patients:

Key Highlights:

- Around half of the cancer patients that have undergone treatment with ImmuPharma’s drug candidate IPP-204106 are in stable condition (their disease has stopped progressing) without any other drug treatment. All the patients that enrolled in the study were suffering from advanced cancer with metastases and had all failed their previous treatments with other existing cancer drugs.

- The third dose level of IPP-204106 has just begun in the next group of patients. ImmuPharma’s clinical trial began last summer and up to now two lower dose levels have been tested. The initial dose level of 1 mg/kg did not show any drug-related side effects. The first patient to be treated in this study is still alive and with stable disease 8 months after starting treatment with ImmuPharma’s cancer compound. The second dose level of 2 mg/kg also did not show any drug-related side effects.

- ImmuPharma has already begun development of the next generation of IPP-204106, the “micro Nucants”. This improved formulation comprising of small particles of the drug candidate has shown an even more impressive efficacy in cancer models.

The clinical trial is taking place in two hospitals in Paris and one hospital in Dijon, in France and is expected to complete in the coming months. Further details and analysis will be provided at the end of the study.

ImmuPharma hopes to start a Phase IIb programme later this year in patients with glioblastoma (brain tumour), hormone-resistant prostate cancer and pancreatic cancer.

Dr Robert Zimmer, MD, PhD, ImmuPharma’s President and Chief Scientific Officer commented: “It is indeed a pleasure and an honour to see cancer patients benefiting from our new drug candidate in our clinical trial. Seeing that the first patient that started treatment with IPP-204106 is still alive and in a stable condition after eight months of treatment gives us confidence in our programme. The improved formulation is a great achievement and further strengthens our position in this field.”

Dimitri Dimitriou, MSc, ImmuPharma’s Chief Executive Officer added: “Having now two drug candidates with positive results in clinical trials is a milestone for ImmuPharma. The latest positive results of our cancer drug candidate clinical trial puts our Company in a good position for further major corporate deals such as the one with our partner Cephalon on LupuzorTM that is now in a large late-stage clinical trial in the United States. This also marks the fifth anniversary of ImmuPharma’s admission to trading on AIM. With our strong cash position and pipeline, we are excited to continue our success.

For further information, please contact: ImmuPharma PLC: Dr Robert Zimmer, President & Chief Scientific Officer + 33 389 32 76 50 Dimitri Dimitriou, Chief Executive Officer +44 20 7152 4080 Richard Warr, Chairman +44 20 7152 4080

Buchanan Communications Lisa Baderoon, Mark Court, Jessica Fontaine +44 20 7466 5000

Panmure, Gordon & Co., NOMAD & Broker Andrew Burnett, Rakesh Sharma +44 20 7459 3600

Espirito Santo Investment Bank James Bromhead, Richard Crawley +44 20 7456 9191



Read at BioSpace.com

   

ADD TO DEL.ICIO.US    ADD TO DIGG    ADD TO FURL    ADD TO STUMBLEUPON    ADD TO TECHNORATI FAVORITES