HiFiBiO SAS Achieves Milestone In Antibody Research Collaboration With Pfizer

CAMBRIDGE, Mass. & PARIS--(BUSINESS WIRE)--HiFiBiO SAS announced today the company has achieved a milestone in its research collaboration with Pfizer Inc., triggering a milestone payment to HiFiBiO.

“The emergence of antibodies as a major therapeutic class has created a need for improved screening approaches using antigen specific B-cells”

The focus of the collaboration, originally signed in 2014, is the development and validation of HiFiBiO’s proprietary, high throughput antibody discovery platform for deep mining of immune repertoires. The platform uses single cell-based screening of entire antibody-secreting B cell populations along with bar coded next generation sequencing and rapid DNA synthesis to identify multiple leads and enable the development of potential optimized antibody candidates.

“Achievement of the milestone is an important step toward establishing the HiFiBiO platform for the discovery of novel, differentiated antibody therapeutics across a broad class of therapeutically important targets,” said Fred Dom, HiFiBiO’s CEO. “The agreement is part of our strategy to establish collaborations with pharmaceutical companies to apply our platform to potentially discover and develop the next generation of antibody therapeutics.”

“The emergence of antibodies as a major therapeutic class has created a need for improved screening approaches using antigen specific B-cells,” said Will Somers, Ph.D., Vice President of Pfizer Global Biotherapeutic Technology. “Our collaborative relationship with HiFiBiO has accelerated the development and potential application of this particular antibody drug discovery approach.”

About HiFiBiO SAS

HiFiBiO SAS is advancing an innovative and integrated discovery engine that creates unparalleled opportunities for discovering novel, differentiated therapeutic antibodies against complex targets. The platform combines high throughput, single cell, functional-based screening of entire B cell populations with barcoded next generation sequencing and rapid DNA synthesis to deeply mine tens of millions of B cells in a typical immune response for rare antibody drugs. The multiple, functionally validated and genetically diverse antibodies produced by HiFiBiO’s approach enable the efficient selection of optimal antibody drug leads. The company has entered into multiple antibody discovery collaborations with leading pharmaceutical companies. Learn more at www.hifibio.com.