Health Diagnostic Laboratory Inc.'s New Diabetes Prevention & Management Panel Incorporates Discovery From Metabolon Researchers

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RESEARCH TRIANGLE PARK, N.C. and RICHMOND, Va., May 29, 2013 /PRNewswire/ -- Health Diagnostic Laboratory, Inc., a CLIA-certified laboratory specializing in advanced cardiovascular and metabolic disease testing and health management, has launched a new blood test for stratifying prediabetic patients based on the Quantose insulin resistance markers discovered by Metabolon, Inc.

Insulin resistance is a primary risk factor for type 2 diabetes and cardiovascular complications, and the Quantose biomarkers have been incorporated into HDL, Inc.'s newly launched Diabetes Prevention & Management Panel, or DPMP. Following a soft-launch period of limited release, development, and test marketing, HDL, Inc. has incorporated the Quantose metabolites seamlessly into DPMP, a 21-test panel available to physicians nationwide beginning this month. Terms of the deal were not disclosed.

"The ability to more accurately identify patients likely to progress to full-blown type 2 diabetes is a powerful tool to help manage the onset of a leading cause of heart disease," said Tonya Mallory, HDL, Inc.'s President, CEO and Co-founder. "The Quantose markers help complete Health Diagnostic Laboratory's DPMP and provide physicians with a more accurate, deeper look at the root causes of prediabetes and diabetes."

Diabetes affects 25.8 million people in the U.S., or 8.3 percent of the population, according to the American Diabetes Association. Nearly one in three U.S. adults almost 80 million people meet the criteria for prediabetes.

The Quantose biomarkers are novel metabolites detected in blood that reflect insulin resistance and detect progression to prediabetes and diabetes earlier than traditional glycemic measures such as HbA1c. By considering insulin resistance, metabolites provide clinicians with a useful tool that goes beyond traditional measures to stratify patients based on their risk for developing diabetes. The Quantosemarkers are particularly useful in identifying prediabetic patients at the greatest risk of disease progression where drug or other interventional therapy may be appropriate. Such a clinical value is well-aligned with American Diabetes Association guidelines, which recommend physicians consider pharmaceutical intervention in high-risk prediabetic patients.

"We are delighted to have an ideal partner in Health Diagnostic Laboratory to bring American clinicians a new tool for identifying and managing patients at risk for developing diabetes," said John Ryals, CEO of Metabolon. "Our expertise in biochemical profiling is reflected in the discovery of the Quantose markers and represents the culmination of many years of research by our scientists. Importantly, if physicians are able to detect high-risk prediabetic patients earlier, it may allow them to initiate therapeutic interventions capable of preventing diabetes and related complications. The launch of Health Diagnostic Laboratory's DPMP using the Quantose markers also represents a significant milestone in Metabolon's evolution from providing biomarker analysis services to discovering cutting-edge metabolomic-based diagnostic markers."

About Health Diagnostic Laboratory, Inc.
Health Diagnostic Laboratory, Inc. (HDL, Inc.) is a leader in health management offering a comprehensive test menu of risk factors and biomarkers for cardiovascular disease, diabetes, and related diseases. HDL, Inc.'s systematic approach identifies factors contributing to disease and provides a basis for effective treatment, allowing physicians to more effectively manage patients. Individuals receive a personalized overview of their risk factors along with intensive counseling from expert Clinical Health Consultants at no additional cost, improving compliance and enhancing satisfaction. HDL, Inc. is a CLIA-certified, CAP-accredited laboratory. For more information, visit myhdl.com.

About Metabolon, Inc.
Metabolon, Inc. is the world leader in the field of metabolomics by pioneering and patenting the industry's leading biochemical biomarker discovery and profiling platform. It has developed the technology to quickly identify and measure all of the biochemicals in a biological sample through its proprietary global processing method. Quantose is the first diagnostic test discovered by Metabolon using its technology. Metabolon has a broad pipeline of diagnostic products in the fields of obesity related conditions and cancer. Metabolon's technology expertise is being embraced by a wide range of pharmaceutical, biotechnology, food and agricultural companies. Metabolytics, its biomarker discovery and analysis business, has completed over 2,500 client studies with more than 500 customers. For more information about Metabolon, please visit www.metabolon.com or contact Eric Button at ebutton@metabolon.com.

SOURCE Health Diagnostic Laboratory, Inc.



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