BioSpace.com

Biotech and Pharmaceutical
News & Jobs
Search the Site
 
   
Biotechnology and Pharmaceutical Channel Medical Device and Diagnostics Channel Clinical Research Channel BioSpace Collaborative    Job Seekers:  Register | Login          Employers:  Register | Login  

NEWSLETTERS
Free Newsletters
Archive
My Subscriptions

NEWS
News by Subject
News by Disease
News by Date
PLoS
Search News
Post Your News
JoVE

CAREER NETWORK
Job Seeker Login
Most Recent Jobs
Browse Biotech Jobs
Search Jobs
Post Resume
Career Fairs
Career Resources
For Employers

HOTBEDS
Regional News
US & Canada
  Biotech Bay
  Biotech Beach
  Genetown
  Pharm Country
  BioCapital
  BioMidwest
  Bio NC
  BioForest
  Southern Pharm
  BioCanada East
  US Device
Europe
Asia

DIVERSITY

INVESTOR
Market Summary
News
IPOs

PROFILES
Company Profiles

START UPS
Companies
Events

INTELLIGENCE
Research Store

INDUSTRY EVENTS
Biotech Events
Post an Event
RESOURCES
Real Estate
Business Opportunities

 News | News By Subject | News by Disease News By Date | Search News
eNewsletter Signup
Miles
Km80.5

   

Hamilton Company Expands the pH Range of Reversed-Phase Chromatography With Highly Efficient HPLC Column


3/12/2013 12:44:04 PM

Reno, Nevada, U.S. (March 12, 2013) – Hamilton’s Laboratory and Sensor Products Division introduces the new Hamilton PRP™-C18 Reversed-Phase HPLC Column, designed to increase the accuracy and quality of separations performed by pharmaceutical companies, environmental scientists, and others.

More than 70% of all drug compounds are amines that are readily separated at high pH. The new Hamilton PRP-C18 Column provides high-efficiency reversed-phase separations over an extended column life in nearly any mobile phase at any pH.

"Mobile phase pH is a powerful tool, particularly for separating neutral forms of amines or other organic bases under alkaline conditions," says Derek Jensen, HPLC product specialist at Hamilton Company. "This greatly simplifies the process of methods development."

The rigid stationary phase of the PRP-C18 is extremely durable, with excellent mechanical (up to 5,000 psi) and thermal stability (greater than 100°C). The flexibility to perform separations at high temperatures and pressures typically shortens run times, allows researchers to use less organic solvent, and increases productivity.

The exceptional chemical and mechanical stability affords scientists high-efficiency separations and an extra-long column life, which saves time and effort typically spent addressing deteriorating column performance and poor sample recovery. Unlike traditional octadecylsilane (ODS) columns with pH limitations, the PRP-C18 can be cleaned with 1 molar sodium hydroxide or 1 molar sulfuric acid to remove contaminants that would normally be irreversibly bound to a silica C18 column. Such pH extremes damage traditional ODS columns, leading to anomalous peak shape and shifting retention times, both of which progressively worsen over the life of the column.

"Chromatographers may be concerned that the robustness to pH extremes, high pressures, and high temperature would come with an inevitable trade-off of efficiency, but that is not the case with the PRP-C18," says Mark Carrier, market segment manager at Hamilton Company. "With this column, Hamilton has created a HPLC column outstanding in both performance and durability."

To learn more about the PRP-C18 Column, visit www.hamiltoncompany.com/PRPC18.

About Hamilton

Hamilton Company is a global leader in the design and manufacture of liquid handling, process measurement, robotics and storage solutions, serving customers in academic and private research laboratories, pharmaceutical and clinical diagnostic companies and government institutions. Hamilton maintains headquarters in Reno, Nevada; Franklin, Massachusetts and Bonaduz, Switzerland, along with subsidiary offices throughout the world. For 60 years, the company has maintained its commitment to building precision and quality into every product. Hamilton is a privately held company with ISO 9001 certification. For more information, www.hamiltoncompany.com.

The PRP™-C18 Reversed-Phase HPLC Column is for research only. Not for use in diagnostic procedures. All trademarks are owned and/or registered by Hamilton Company in the U.S. and/or other countries. For details visit, www.hamiltoncompany.com/trademarks.

Enc. Graphics, page 2 & 3

Link to this release at: www.hamiltoncompany.com/News/pressrelease.php?id=47&r=

Mark Carrier

Chromatography Market Segment Manager

Hamilton HPLC Columns and Accessories

Product inquiries

775-858-3000 ext. 456

mark.carrier@hamiltoncompany.com

Annette Summers

PR Consultant for Hamilton Company

GeneCom Group

Press inquiries

(925) 519-0608

annette@genecom.net



Read at BioSpace.com

   

ADD TO DEL.ICIO.US    ADD TO DIGG    ADD TO FURL    ADD TO STUMBLEUPON    ADD TO TECHNORATI FAVORITES