Given Imaging Ltd. Release: Study Shows Endoluminal Image Analysis With Capsule Endoscopy Is an Effective Test for Assessing Intestinal Motility

YOQNEAM, ISRAEL--(Marketwire - November 20, 2008) - Given Imaging Ltd. (NASDAQ: GIVN) (TELAVIV: GIVN) today announced that a study published in the October issue of Gastroenterology confirms the potential of a new approach to measuring small bowel intestinal motility based on video images obtained through small bowel capsule endoscopy. Patients with intestinal dysmotility may suffer from pain, bloating, nausea or vomiting. This condition is generally related to weak or disorganized muscle contractions in the intestine. Small bowel manometry, the current standard of care, is a relatively complex, invasive and unpleasant procedure that requires specialized clinical expertise in order to interpret its findings. As a result, it is not widely available. A new, minimally invasive technique to evaluate intestinal motility utilizes a sophisticated, automated analysis of the images obtained during capsule endoscopy and could prove to be an easier and more convenient tool than manometry for both the patient and the physician. It could also reduce the number of diagnostic tests required to evaluate patients by providing one procedure to analyze both intestinal structure and function at the same time.