BioSpace.com

Biotech and Pharmaceutical
News & Jobs
Search the Site
 
   
Biotechnology and Pharmaceutical Channel Medical Device and Diagnostics Channel Clinical Research Channel BioSpace Collaborative    Job Seekers:  Register | Login          Employers:  Register | Login  

NEWSLETTERS
Free Newsletters
Archive
My Subscriptions

NEWS
News by Subject
News by Disease
News by Date
PLoS
Search News
Post Your News
JoVE

CAREER NETWORK
Job Seeker Login
Most Recent Jobs
Browse Biotech Jobs
Search Jobs
Post Resume
Career Fairs
Career Resources
For Employers

HOTBEDS
Regional News
US & Canada
  Biotech Bay
  Biotech Beach
  Genetown
  Pharm Country
  BioCapital
  BioMidwest
  Bio NC
  BioForest
  Southern Pharm
  BioCanada East
  US Device
Europe
Asia

DIVERSITY

INVESTOR
Market Summary
News
IPOs

PROFILES
Company Profiles

START UPS
Companies
Events

INTELLIGENCE
Research Store

INDUSTRY EVENTS
Biotech Events
Post an Event
RESOURCES
Real Estate
Business Opportunities

 News | News By Subject | News by Disease News By Date | Search News
eNewsletter Signup
Miles
Km80.5

   

GeneTex, Inc. to Launch a New Primary Antibody Against HIF1a


8/28/2012 10:00:30 AM

IRVINE, Calif., Aug. 28, 2012 /PRNewswire/ -- GeneTex, Inc., a leading manufacturer of antibodies, has announced that they will be launching a new antibody against HIF1a (hypoxia-inducible factor 1alpha).

(Photo: http://photos.prnewswire.com/prnh/20120828/AQ63427)

(Logo: http://photos.prnewswire.com/prnh/20111129/LA13485LOGO-b)

Hypoxia, a physiological state characterized by reduced oxygen levels, impacts metabolism, angiogenesis, vasodilation and erythropoiesis through the HIF1a transcription factor. In addition to being a natural physiological process, hypoxia and the subsequent accumulation of HIF1a have been shown to significantly contribute to the pathophysiology of multiple diseases including cancer, pulmonary hypertension, myocardial and cerebral ischemia, congenital heart disease and chronic obstructive pulmonary disease. When oxygen becomes limited, prolyl hydroxylase is inhibited, which leads to HIF1a accumulation and translocation to the nucleus. HIF1a then activates transcription of various genes including VEGFA, Glut1 and CA9 that are responsible for the cellular hypoxia response. Therefore, antibodies that can accurately detect HIF1a are valuable research tools for the study of hypoxia and hypoxia-related diseases.

"HIF1a is an important target for biomedical research, but unfortunately many of the antibodies that are currently on the market have been plagued by specificity and stability issues," says Dr. Stephen Kendall. "GeneTex's new HIF1a antibody can withstand multiple freeze/thaw cycles without losing its sensitivity."

GeneTex is proud to introduce this superior antibody against HIF1a that is both highly stable and specific. This antibody has been fully validated for immunocytochemistry/immunofluorescence, immunoprecipitation and western blotting applications.

For additional information on GeneTex, Inc. and its hypoxia antibodies, please call toll-free 877-GENETEX (436-3839) or visit http://www.genetex.com/HIF1-alpha-antibody-GTX127309.html.

About GeneTex, Inc.
GeneTex, Inc. is an antibody manufacturer founded by a group of internationally renowned academic scientists in 1997. They strive to produce the highest quality antibodies and reagents. Their primary antibodies and secondary antibodies are created through a process involving extensive research, development and validation. GeneTex's catalog has grown to over 55,000 primary antibodies and all are backed by a 100% Satisfaction Guarantee.

Corporate Mission
We strive to serve and accelerate life science research by creating essential life science tools where quality can be found in every vial.

SOURCE GeneTex, Inc.



Read at BioSpace.com

   

ADD TO DEL.ICIO.US    ADD TO DIGG    ADD TO FURL    ADD TO STUMBLEUPON    ADD TO TECHNORATI FAVORITES