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First Step Towards Switching Off Breast Cancer And Leukaemia, Garvan Institute of Medical Research Study


8/8/2008 8:09:33 AM

EurekAlert -- Australian scientists have identified a way to 'switch off' a molecule, a key player in the molecular processes that trigger breast cancer and certain forms of leukaemia. The molecule, known as Gab2, operates downstream of a major breast cancer oncogene, HER2, the target of the drug Herceptin. A research team from the Garvan Institute of Medical Research, led by Professor Roger Daly, has found a novel way of blocking signals to and from Gab2, preventing it from fulfilling its role in cell proliferation. The finding is published online today in the EMBO Journal.

Read at EurekAlert!

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