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First Single Gene Mutation Shown to Result in Type 1 Diabetes, University Hospital in Basel Study


3/6/2013 7:31:12 AM

A JDRF-funded study out of Switzerland has shown that a single gene called SIRT1 may be involved in the development of type 1 diabetes (T1D) and other autoimmune diseases. The study, "Identification of a SIRT1 Mutation in a Family with Type 1 Diabetes," was published March 5 in Cell Metabolism and represents the first demonstration of a monogenetic defect leading to the onset of T1D.

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