BioSpace.com

Biotech and Pharmaceutical
News & Jobs
Search the Site
 
   
Biotechnology and Pharmaceutical Channel Medical Device and Diagnostics Channel Clinical Research Channel BioSpace Collaborative    Job Seekers:  Register | Login          Employers:  Register | Login  

NEWSLETTERS
Free Newsletters
Archive
My Subscriptions

NEWS
News by Subject
News by Disease
News by Date
PLoS
Search News
Post Your News
JoVE

CAREER NETWORK
Job Seeker Login
Most Recent Jobs
Browse Biotech Jobs
Search Jobs
Post Resume
Career Fairs
Career Resources
For Employers

HOTBEDS
Regional News
US & Canada
  Biotech Bay
  Biotech Beach
  Genetown
  Pharm Country
  BioCapital
  BioMidwest
  Bio NC
  BioForest
  Southern Pharm
  BioCanada East
  US Device
Europe
Asia

DIVERSITY

INVESTOR
Market Summary
News
IPOs

PROFILES
Company Profiles

START UPS
Companies
Events

INTELLIGENCE
Research Store

INDUSTRY EVENTS
Biotech Events
Post an Event
RESOURCES
Real Estate
Business Opportunities

 News | News By Subject | News by Disease News By Date | Search News
eNewsletter Signup
Miles
Km80.5

   

Febit, Inc. First to Offer Newly Published Mouse Genome on a Chip for DNA/RNA Detection and Enrichment


6/30/2009 8:24:35 AM

febit Technology Enables the Conversion of New Sequence Data into Biochips for Gene Expression Profiling and Sequence Capture for Next-Generation Sequencing Within Days

LEXINGTON, Mass. and HEIDELBERG, Germany, June 29 /PRNewswire/ -- febit holding gmbh announced today the launch of the first biochip on the market covering the newly published whole mouse genome. The biochip from febit enables up-to-date profiling and enrichment of genes and SNPs of interest using Gene Expression Profiling, SNP-Detection, ncRNA analysis as well as targeted enrichment of genes for Next-Generation Sequencing (NGS).

Professor Christian Koerner from the University Hospital for Pediatrics in Heidelberg (Germany) and customer of febit's new mouse biochip, said: "It will be helpful and an advance for our research to use a whole genome microarray based on the most recent data available which have been published only weeks ago. This array allows the performance of a microarray expression profiling as well as a targeted Next-Generation Sequencing at the current state of the art."

In the near future, Next-Generation Sequencing technologies will lead to a rising number of completed genomes of model organisms and other species of interest, as demonstrated by the updated mouse genome. This accelerated development will generate a variety of tools available in the short term for the application of the new data into experiments. febit's Geniom(R) Technology represents the most efficient option for transforming digital genetic sequence information directly into a fully-applicable microarray and sequence capture biochip. The microfluidic biochips and flexible probe synthesis guarantee instant access to the latest sequence updates within only days after publication or request.

New mouse genome assembly

The mouse (mus musculus) is the most important and well-established model for the study of human disease and mammalian development. At the end of May 2009, D.M. Church et al. published in the journal PLoS Biology a complete, high-quality genome assembly that contains over 139 Mb more of novel sequence compared to previously available mouse genome drafts. This brand-new, finished mouse genome, which is now available on febit's microarrays, closes more than 175,000 gaps, completes the list of protein-coding genes to a number of 20,210 and identifies 439 long, non-coding RNAs. Thus, a complete analysis of protein gene expression, microRNA profiles and expression patterns of long non-coding RNAs is possible and can reveal many previously hidden secrets of mammalian biology and disease processes.

Flexibel technology for fast-paced research

febit's Geniom Technology provides turnkey solutions with established protocols and streamlined workflows, enabling all major RNA profiling applications as well as targeted Next-Generation Sequencing. HybSelect, sequence-specific DNA enrichment is enabled through hybridization and elution of high-value target regions by utilizing febit's flexible Geniom Biochips. The enriched DNA is ideally suited for cost-effective targeted sequencing on Next-Generation Sequencing platforms. With its new HybSelect Biochip for the mouse genome, febit complements its offering for up-to-date sequence analyses in the field of mammalian research. Biochips for other models will follow as soon as the appropriate sequence analyses are completed. febit biochips are available for analysis at the Geniom RT Analyzer or as a full service from febit.

About febit

febit develops, produces and markets flexible automated solutions for enabling biochip applications in Life Sciences. febit's product portfolio includes various instruments, optimized assays and bioanalytical services, complemented by bioinformatics software and consulting.

For its main applications - HybSelect, febit's innovative DNA capture method for Next-Generation-Sequencing and protein-coding or non-coding transcriptome profiling - the highly advanced microfluidics of the patented Geniom Biochip offers the highest degree of automation, flexibility and efficiency available.

For more information, please visit www.febit.com.

CONTACT: Eva Sterzel of febit group, +49(0)6221-6510-300,
eva.sterzel@febit.com; or Martina Schwarzkopf of Russo Partners,
+1-212-845-4292, martina.schwarzkopf@russopartnersllc.com

Web site: http://www.febit.com/



Read at BioSpace.com

   

ADD TO DEL.ICIO.US    ADD TO DIGG    ADD TO FURL    ADD TO STUMBLEUPON    ADD TO TECHNORATI FAVORITES