Epeius Biotechnologies Corporation: Scientists Rediscover Gene Target for Cancer Therapy Rexin-G Receives High-tech Validation as Strategic Anti-cancer Agent
SAN MARINO, Calif., Dec. 15 /PRNewswire/ -- Epeius Biotechnologies Corporation, an emerging leader in the field of targeted genetic medicine, gained international validation of the cutting-edge science behind its lead oncology product, Rexin-G, when scientists around the world rediscovered the Cyclin G1 gene to be a major locus of cancer pathogenesis and disease progression, and thus a prime target for anti-cancer therapies. Recently, scientists at the NIH National Cancer Institute investigating the role of microRNAs (miRNAs) in tumor development and their utility to serve as biomarkers for cancer diagnosis and prognosis identified one particular species of miRNA (designated miR-122) that was linked to both the development and the aggressiveness of liver cancer (Coulouran et al., Oncogene, 2009).
The finding that the natural suppression of the Cyclin G1 gene is lost in cancer cells is not at all surprising to scientists at Epeius Biotechnologies, who first identified the human Cyclin G1 gene as a proto-oncogene in 1994, demonstrated its therapeutic potential in a comprehensive series of landmark studies (1995-2005), and designed the sophisticated dominant-negative "knockout" construct embodied in the powerful anti-cancer agent Rexin-G (see Gordon and Hall, Intl. J. Oncology, 2009).
Epeius Biotechnologies Corporation is a privately held biopharmaceutical company dedicated to the advancement of genetic medicine with the development and commercialization of its leading oncology products and its tumor-targeted gene delivery systems. Rexin-G, a tumor-targeted anti-cancer agent that is approved for use against all solid tumors by the Philippine FDA, and has recently received three Orphan Drug priorities and Fast Track designation by the U.S. FDA. Please visit us at http://www.epeiusbiotech.com .
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CONTACT: Erlinda M. Gordon, M.D. of Epeius Biotechnologies Corporation,
+1-626-441-6695, egordon@epeiusbiotech.com
Web site: http://www.epeiusbiotech.com/