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Enzyme Enhances, Erases Long-Term Memories in Rats, SUNY Downstate Medical Center Study



3/4/2011 7:11:33 AM

(PhysOrg.com) -- Even long after it is formed, a memory in rats can be enhanced or erased by increasing or decreasing the activity of a brain enzyme, say researchers supported, in part, by the National Institutes of Health. "Our study is the first to demonstrate that, in the context of a functioning brain in a behaving animal, a single molecule, PKMzeta, is both necessary and sufficient for maintaining long-term memory," explained Todd Sacktor, of the SUNY Downstate Medical Center, New York City, a grantee of the NIH’s National Institute of Mental Health.

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