BioSpace.com

Biotech and Pharmaceutical
News & Jobs
Search the Site
 
   
Biotechnology and Pharmaceutical Channel Medical Device and Diagnostics Channel Clinical Research Channel BioSpace Collaborative    Job Seekers:  Register | Login          Employers:  Register | Login  

NEWSLETTERS
Free Newsletters
Archive
My Subscriptions

NEWS
News by Subject
News by Disease
News by Date
PLoS
Search News
Post Your News
JoVE

CAREER NETWORK
Job Seeker Login
Most Recent Jobs
Browse Biotech Jobs
Search Jobs
Post Resume
Career Fairs
Career Resources
For Employers

HOTBEDS
Regional News
US & Canada
  Biotech Bay
  Biotech Beach
  Genetown
  Pharm Country
  BioCapital
  BioMidwest
  Bio NC
  BioForest
  Southern Pharm
  BioCanada East
  US Device
Europe
Asia

DIVERSITY

INVESTOR
Market Summary
News
IPOs

PROFILES
Company Profiles

START UPS
Companies
Events

INTELLIGENCE
Research Store

INDUSTRY EVENTS
Biotech Events
Post an Event
RESOURCES
Real Estate
Business Opportunities

 News | News By Subject | News by Disease News By Date | Search News
eNewsletter Signup
Miles
Km80.5

   

EKF diagnostic GmbH Molecular Launches Cancer Gene Detection Technologies at American Society of Clinical Oncology 2013


5/21/2013 9:33:13 AM

Staying up-to-date has never been simpler. Sign up for the free GenePool newsletter today!

Cardiff, UK – 21 May 2013 – EKF Diagnostics, the point-of-care diagnostics business, has announced the launch of EKF Molecular Diagnostics’ PointMan™ DNA Enrichment kits at ASCO 2013, 31st May – 4th June, Chicago. The global launch will comprise three kits for enriching mutations in BRAF, KRAS and EGFR T790M genes associated with skin melanoma, colorectal and lung cancers. PointMan kits offer highly-specific and ultra-sensitive enrichment of mutant genes in a background of wild-type (normal) genes that is unmatched by existing technologies.

The launch of the new PointMan kits on Stand 19117 is the first new product introduction since EKF’s acquisition of 360 Genomics Limited and the establishment of EKF Molecular Diagnostics in March 2013. EKF Molecular was set up to offer innovative products with the potential to change current DNA extraction and detection practices, in order to best support the fast growing companion diagnostics market.

PointMan, is a real-time PCR technology that provides reliable and extremely sensitive detection for cancer mutations. It is highly efficient in amplifying the target sequence of interest, whilst suppressing amplification of the wild-type. The resulting sample is effectively enriched for the mutation, thereby having the potential to offer industry leading sensitivity in a wide variety of sample types.

PointMan DNA enrichment kits can also be used to enrich all mutant sequences within the gene of interest using a single set of reagents, unlike competing technology that requires a separate reagent set for each mutation within a gene sequence. These kits offer fast, efficient and cost effective enrichment of mutant gene sequences for researchers in the pharmaceutical industry developing anti-cancer therapies. At ASCO, EKF Molecular Diagnostics will also premiere its pipeline of PointMan enrichment kits currently in development for other cancer-related mutations.

The three PointMan kits initially being launched for the Research Use Only market, with planned diagnostic registration in Europe in 2014, are:

PointMan BRAF DNA Enrichment Kit

The BRAF gene has proven utility in the treatment of melanoma, as well as colorectal cancer.

PointMan KRAS DNA Enrichment Kit

The KRAS gene has proven utility in the treatment of colorectal cancer.

PointMan EGFR T790M DNA Enrichment Kit

T790M mutation in EGFR (epidermal growth factor receptor) has been associated with about 50% of patients who develop resistance to EGFR targeted therapies in non-small cell lung cancer.

Andrew Webb, Chief Executive Officer of EKF Molecular, said: “The launch of these three kits, which are the first in a line of further expected PointMan product launches, comes ahead of schedule and represents step one in our operational development plan for the newly established EKF Molecular Diagnostics.”

For more information please visit www.ekfdiagnostics.com. This release is also available online at:

http://www.ekfdiagnostics.com/news.aspx?id=95.

About EKF Diagnostics

www.ekfdiagnostics.com

EKF Diagnostics Holdings plc specialises in the development, production and worldwide distribution of point-of-care blood analysers for use in the detection and management of diabetes, anaemia, lactate and kidney related diseases. Its new Molecular division focuses on molecular and companion diagnostics.

Point-of-care diagnostics: EKF Diagnostics’ expertise covers the entire in vitro diagnostics chain, from fermentation and enzyme production, to liquid reagent manufacture, design and building of world-class diagnostic devices, and distribution of rapid test kits for infectious diseases and pregnancy. The EKF analyser range is used widely in GP surgeries, pharmacies, blood banks, sports clinics, hospitals and laboratories for glucose, lactate, haemoglobin, haematocrit and HbA1c measurement.

Companion Diagnostics: In March 2013 EKF set up a new division to focus on molecular and companion diagnostics - EKF Molecular Diagnostics develops technologies for cancer gene detection. Through its acquisition of UK-based 360 Genomics and by offering innovative products with the potential to change current DNA extraction and detection practices, EKF is addressing the fast growing companion diagnostics market.

EKF Diagnostics products are sold in more than 100 countries around the globe. EKF Diagnostics’ strengths lie in its multi-national research and manufacturing facilities, teams of experienced analysts and engineers in Germany, Ireland, USA and the UK, and a board led by some of world’s foremost authorities in medical diagnostics.



Help employers find you! Check out all the jobs and post your resume.


Read at BioSpace.com

   

ADD TO DEL.ICIO.US    ADD TO DIGG    ADD TO FURL    ADD TO STUMBLEUPON    ADD TO TECHNORATI FAVORITES