Do Clinical Trials Work? Forbes Reviews NY Times' Piece

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For any new drug to be approved, it must be proven to be both safe and effective in large clinical trials in patients. Biopharmaceutical companies have been running these trials, known as randomized clinical trials (RCTs), for decades. RCTs are run in such a way that both the patients and doctors are “blinded” in that they don’t know if the patient is receiving the study drug, a comparator drug, or a placebo. Once the study has been completed, the “blind” is broken and the results are analyzed to determine the effects of the new drug with respect to the comparator.

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