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Diamyd Medical AB's NTDDS Technology Effective Against Diabetes Pain

9/2/2008 6:57:53 AM

STOCKHOLM, Sweden--(BUSINESS WIRE)-- Diamyd Medical reports that its Nerve Targeting Drug Delivery System (NTDDS) expressing enkephalin, is effective in preclinical models of diabetes pain.

Dr. David Fink, published in the scientific journal “Journal of Neuroscience” that Diamyd Medical’s proprietary NTDDS platform, expressing enkephalin, effectively relieves pain due to diabetes in animals. The NTDDS platform allows focal delivery of the human enkephalin gene directly to nerves experiencing pain.

”These new data indicate that not only is the NTDDS platform with enkephalin effective at reducing pain, it reverses the root cause of diabetes related pain. This means that the approach is not just pain relief, but local pain prevention”, says Darren Wolfe, President of Diamyd Inc.

Elisabeth Lindner, President and CEO of Diamyd Medical, states “We have positioned Diamyd Medical as a diabetes company. These exciting results give us the opportunity to expand our product portfolio to include a third diabetes related product, NP2”.

Diamyd’s product NP2 (NTDDS expressing enkephalin), is currently in Phase I clinical safety studies. Dr. Fink, Professor and chair of the Department of Neurology at the University of Michigan, is the Principal Investigator for this study.

Diamyd Medical’s diabetes product portfolio includes NP2, Diamyd® vaccine for type 1 diabetes and Diamyd® vaccine for LADA.

Diamyd Medical is a Swedish biopharmaceutical company focusing on development of pharmaceuticals for treatment of autoimmune diabetes and its complications. The company’s most advanced project is the GAD-based drug Diamyd® for type 1 diabetes and for which Phase III trials are ongoing in both the US and Europe. Furthermore, the company has initiated clinical studies within chronic pain, using its Nerve Targeting Drug Delivery System (NTDDS). The company has also out-licensed the use of GAD for the treatment of Parkinson’s disease.

Diamyd Medical has offices in Sweden and in the US. The share is quoted on the OMX Stockholm Nordic Exchange (ticker: DIAM B) and on OTCQX in the US (ticker: DMYDY) administered by the Pink Sheets and the Bank of New York (PAL). Further information is available on the company’s web site:

This information is disclosed in accordance with the Securities Markets Act, the Financial Instruments Trading Act or demands made in the exchange rules.

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Diamyd Medical AB (publ.) Elisabeth Lindner, President and CEO Phone: +46-8-661 0026 or Diamyd Inc. Darren Wolfe, President Phone +1-412-770-1310 or For pictures and press material, please contact: Diamyd Medical AB (publ) Sonja Catani, Chief Communications Officer Phone: +46-8-661 00 26 or Diamyd Medical AB (publ.) Tel: +46 8 661 00 26 Fax: +46 8 661 63 68 E-post:

Source: Diamyd Medical

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