Debiopharm and Airmid Sign Option and License Agreement for the Development of Debio 0824, an ShK Peptide for Autoimmune Disorders
In vitro data show that ShK peptides discovered by Airmid's founders are potent and selective Kv1.3 inhibitors with a strong potential to treat autoimmune diseases. Preclinical data show that ShK peptides suppress the activation and inhibit the proliferation of auto-reactive human and rat T effector memory cells at concentrations 20 to 80 times lower than the proliferation of naive and central memory T cells. Moreover, ShK peptides significantly improve disease symptoms in animal models of several autoimmune disorders. This suggests that an ShK peptide might prove useful in the therapy of autoimmune disorders - in particular, psoriasis, multiple sclerosis and rheumatoid arthritis - without significant impairment of the immune response.
About Debiopharm Group
Debiopharm Group is a global biopharmaceutical development specialist that in-licenses promising biologics and small molecule drug candidates. Debiopharm develops its products for global registration and maximum commercial potential for out-licensing to pharmaceutical partners for sales and marketing. Debiopharm independently funds the worldwide development of all of its products while providing expertise in pre-clinical and clinical trials, manufacturing, drug delivery and formulation, and regulatory affairs.
Founded in 1979 and headquartered in Lausanne, Switzerland, Debiopharm has developed three products with global combined sales in excess of $2.65 billion in 2007.
For more information on Debiopharm Group, please visit: http://www.debiopharm.com.
About Airmid
Airmid is a virtual pharmaceutical start-up focused on developing and commercialising novel, safer, more effective treatments for all autoimmune disorders. Airmid's preclinical drug candidates include both peptide and small molecule inhibitors of the potassium channel protein, Kv1.3, which is highly expressed in auto-reactive T lymphocytes.
For more information on Airmid, please visit: http://www.airmid.com.
Debiopharm S.A. Contacts Kim Bill VP Corporate Development Tel: +41(0)21-321-01-11 Fax: +41(0)21-321-01-69 kbill@debiopharm.com
Additional Media Contacts
In London Maitland Brian Hudspith Tel: +44(0)20-7379-5151 bhudspith@maitland.co.uk
In New York Russo Partners, LLC Wendy Lau Tel: +1-212-845-4272 Fax: +1-212-845-4260 wendy.lau@russopartnersllc.com
Source: The Debiopharm Group