Welwyn Garden City, UK – 25 October 2012 – Cresset, innovative provider of software and services, announces the release of torchV10, a complete desktop molecular design and 3D SAR tool for medicinal chemists.
torchV10 uses molecular fields to show the binding patterns of your compounds. This protein’s eye view gives clear insights into the causes of biological activity.
Working with torchV10, medicinal chemists can see how to optimize the shape and electrostatic properties of their series, and rapidly identify the best next molecule to synthesize.
Cresset CEO, Dr Robert Scoffin said, “We believe that molecular fields are the most intuitive way of assessing biological activity. We would like every chemist to access the power of fields so that they can truly understand the mechanisms by which their leads interact with targets. torchV10 is such an easy to use desktop tool that it brings these insights within the reach of every medicinal chemist.”
[CAPTION: torchV10 is a complete desktop molecular design and Structure Activity Relationship (SAR) tool that brings the power of fields within the reach of every chemist]
Medicinal chemists, research managers, academics and computational chemists who want to find out more about torchV10 can register for a free introductory webinar at http://www.cresset-group.com/2012/10/webinar-torchv10/.
torchV10 is a powerful molecule design and 3D SAR tool for medicinal chemists. Use it to take leaps in compound design while maintaining or improving biological activity. Compare actives and inactives from multiple series, gathering the best from each. Employ this knowledge in the next design iteration using the in-built molecular editor for immediate feedback.
• Perfect the design of new lead compounds, exploring a range of lead optimization ideas.
• Get the most from your lab time by prioritizing compounds for synthesis.
• Design focused libraries for synthesis or initial screening.
• View ADME profiles and off-target activity prediction on all designs.
For further information on the complete range of software and services available from Cresset, please visit www.cresset-group.com, follow Cresset on Twitter (@cressetgroup) or join their LinkedIn group.
About Cresset Group Ltd
Cresset develops software for calculating and comparing the molecular field characteristics of chemical compounds. Field technology uses the surface properties of molecules to evaluate their activities and properties, rather than relying on 2D structure similarity, which enables Cresset’s users to find more interesting, novel and relevant results than other methods. Cresset’s fields provide a smarter, structure independent way of hit-finding, lead switching and lead optimization in drug discovery and other chemistry-based research projects. Cresset’s Field technologies have been successfully applied to a very wide range of target classes, with and without structural information, on over 100 projects for major pharmaceutical and biotechnology companies. www.cresset-group.com