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Compugen Ltd. (CGEN) Announces Validation Results for a Second Potential Immune Checkpoint Target for Cancer Immunotherapy


6/27/2012 9:26:17 AM

TEL AVIV, Israel--(BUSINESS WIRE)--Compugen Ltd. (NASDAQ: CGEN) announced today results demonstrating the therapeutic potential of CGEN-15022, a Compugen-discovered B7/CD28-like membrane protein, as an immune checkpoint target for treatment of multiple cancers. The results indicate that CGEN-15022 is expressed in numerous types of epithelial cancers with significant unmet clinical needs, such as liver, colorectal, lung and ovarian cancers. These findings, together with previously disclosed results pointing to its negative costimulatory activity, strongly support CGEN-15022’s potential as a compelling drug target for treatment of these cancers through monoclonal antibody (mAb) therapy, an area of great interest to the pharmaceutical industry.

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