BioSpace.com

Biotech and Pharmaceutical
News & Jobs
Search the Site
 
   
Biotechnology and Pharmaceutical Channel Medical Device and Diagnostics Channel Clinical Research Channel BioSpace Collaborative    Job Seekers:  Register | Login          Employers:  Register | Login  

NEWSLETTERS
Free Newsletters
Archive
My Subscriptions

NEWS
News by Subject
News by Disease
News by Date
PLoS
Search News
Post Your News
JoVE

CAREER NETWORK
Job Seeker Login
Most Recent Jobs
Browse Biotech Jobs
Search Jobs
Post Resume
Career Fairs
Career Resources
For Employers

HOTBEDS
Regional News
US & Canada
  Biotech Bay
  Biotech Beach
  Genetown
  Pharm Country
  BioCapital
  BioMidwest
  Bio NC
  BioForest
  Southern Pharm
  BioCanada East
  US Device
Europe
Asia

DIVERSITY

INVESTOR
Market Summary
News
IPOs

PROFILES
Company Profiles

START UPS
Companies
Events

INTELLIGENCE
Research Store

INDUSTRY EVENTS
Biotech Events
Post an Event
RESOURCES
Real Estate
Business Opportunities

 News | News By Subject | News by Disease News By Date | Search News
eNewsletter Signup
Miles
Km80.5

   

CIT Joins EUR 10 Million R&D Project Funded By EU and European Cosmetic Industry


1/13/2011 10:51:37 AM

Evreux, France, January 13, 2011 - CIT, a leading European non-clinical CRO, today announced it will be joining with other partners in a five-year joint research and development project to address the unmet need for test methods for predicting toxicity of drugs, chemicals and cosmetic ingredients. The project is called ScreenTox (Stem Cells for Relevant, Efficient, Extended & Normalised Toxicology). The partners will receive funding within the Health Programme of the European Commission's 7th RTD Framework Programme.

CIT is one of 14 industrial and academic partners in the project, which is coordinated by Inserm, the French National Institute for Health and Medical Research. The “ScreenTox” project will be funded as part of a research cluster with an overall budget of EUR 50 million. This cluster covers seven projects and represents a unique joint effort from the European Commission and the European Cosmetic Association (COLIPA).

In the development of products for use by humans, it is vital to identify compounds with toxic properties at an early stage of their development, in order to avoid spending time and resources on unsuitable and potentially unsafe candidate products. Human pluripotent stem cells offer an unparalleled opportunity to create a wide variety of human cell-based test systems because these cells may be expanded indefinitely and triggered to differentiate into any cell type. The “ScreenTox” project aims at making use of these two attributes in order to optimize current processes and develop novel methods to achieve functional differentiation of human-based target cells in vitro.

The project recognizes a major paradigm shift in predictive toxicology that pluripotent stem cells will permit in the coming years. “The evaluation of toxicants calls for new models that will allow assessing toxicity pathway responses in vitro,” said Marc Peschanski, a leading scientist in the field of toxicity and coordinator of the network. “Derivatives of pluripotent stem cell lines are likely to be the best candidates to implement this new strategy, as these most relevant and reliable model systems can also be robust and scalable in order to meet the challenges of industrial-scale screens.”

"ScreenTox has the potential to generate a huge leap forward in toxicity testing as it combines three key factors: a wide range of international scientific expertise and industry know-how as well as substantial financial investment,” said Roy Forster, CIT's scientific director. “We believe that ScreenTox will demonstrate advantages in using stem cells to assess how safe new products will be for use on humans, and in refining, reducing or even replacing the use of animals for testing.”

About CIT http://www.citox.com

CIT is a science-driven, independent, non-clinical contract research organization (CRO) specialized in safety and health research. Founded in 1969, CIT has carried out a vast number of projects for international companies on human and veterinary pharmaceuticals, biotechnology, chemicals, agrochemicals and consumer products. It has contributed to many product registrations around the world.

With a staff of 350, CIT offers a full range of research in general toxicology, reproductive toxicology, carcinogenicity, pharmacokinetics and safety pharmacology. The company also carries out research into genetic toxicology, in vitro testing and toxicogenomics.

Its 20,000 sq m (215,000 sq ft) facilities located in Normandy, one hour from Paris, France, house all principal laboratory animal species to the highest standards. Laboratory facilities include analytical chemistry and bioanalysis, clinical pathology, genomics and histology. Support facilities include archives and plant buildings. The company is GLP and AAALAC certified.

More than half the company’s business comes from international customers. Overall, 80 per cent of revenues are in the pharmaceutical and biotechnology sector. Biotechnology and start-up companies alone account for 50 per cent. The company has a world-class team of top-level management in scientific, financial and business activities.

Lynne Chapman ANDREW LLOYD & ASSOCIATES http://www.ala.com lynne@ala.com

Brighton Business Centre 95 Ditchling Road Brighton BN1 4ST ENGLAND Tel: +44 1273 675100 Fax: +44 1273 675400

55 rue Boissonade 75014 Paris FRANCE Tel: +33 1 56 54 07 00 Fax: +33 1 56 54 07 01

INTERNATIONAL TECHNOLOGY MARKETS, STRATEGY & COMMUNICATION



Read at BioSpace.com

CIT
 
 

ADD TO DEL.ICIO.US    ADD TO DIGG    ADD TO FURL    ADD TO STUMBLEUPON    ADD TO TECHNORATI FAVORITES