Changes In Adult Stem Cells May Underlie Rare Genetic Disease Associated With Accelerated Aging, National Cancer Institute Study

NCI -- Adult stem cells may provide an explanation for the cause of a Hutchinson-Gilford Progeris Syndrome (HGPS), a rare disease that causes premature aging in children, according to researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH). These findings, the first to indicate a biological basis for the clinical features of progeria, may also provide new insights into the biological mechanisms of normal aging. The results were published in the March, 2008, issue of Nature Cell Biology.

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