Cell Signaling Technology, Inc. Announces License in Personalized Cancer Diagnostics

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DANVERS, Mass.--(BUSINESS WIRE)--Cell Signaling Technology, Inc. (CST) of Danvers, MA, announced today that it has granted Cepheid, Inc., a worldwide non-exclusive license to CST patent rights relating to the detection of ALK gene rearrangements for the field of PCR (polymerase chain reaction) diagnostic testing. Cepheid will develop a test, which is intended to identify non-small cell lung cancer (NSCLC) patients with anaplastic lymphoma kinase (ALK) gene rearrangements. Lung cancer is the world's leading cause of cancer death with more than 1.6 million new cases diagnosed each year. About 85 percent of lung cancer patients have the non-small cell type and are usually diagnosed with advanced disease and a very low survival rate. Preliminary epidemiology suggests that approximately 3–5 percent of NSCLC patients have tumors positive for the ALK fusion gene.

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