Bristol-Myers Squibb Release: First Presentation Of Two-Year Overall Survival Data For Opdivo (Nivolumab) In Combination With Yervoy (Ipilimumab) Showed Superior Efficacy Versus Yervoy Alone In Advanced Melanoma

PRINCETON, N.J.--(BUSINESS WIRE)--Bristol-Myers Squibb Company (NYSE:BMY) announced today first time presentation of overall survival data from CheckMate -069, a Phase 2 trial and the first randomized study to evaluate the Opdivo and Yervoy combination regimen in patients with previously untreated advanced melanoma. In the trial, the Opdivo and Yervoy combination regimen demonstrated a two-year overall survival (OS) rate of 69% compared to 53% for Yervoy alone (HR=0.58 [95% CI: 0.31-1.08]) in patients with BRAF wild-type advanced melanoma. Overall survival was an exploratory endpoint in this trial. The safety profile of the Opdivo and Yervoy combination regimen in this study was consistent with previously reported studies. These data will be presented today as an oral presentation at the American Association for Cancer Research (AACR) 2016 Annual Meeting during the Immuno-Oncology Clinical Trials I Plenary Session from 2:15 – 4:00 P.M. CT in New Orleans, Louisiana (Late-Breaking and Clinical Trial Abstract #CT002).