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Bowel Cancer Caused by Faulty Genes and Iron Levels, University of Birmingham Study



8/10/2012 7:23:30 AM

HIGH LEVELS of iron could raise the risk of bowel cancer by switching on a key pathway in people with faults in a critical anti-cancer gene, according to a study published in Cell Reports* today (Thursday). Cancer Research UK scientists, based at the University of Birmingham and the Beatson Institute for Cancer Research in Glasgow, found bowel cancers were two to three times more likely to develop in mice with a faulty APC gene that were fed high amounts of iron compared to mice who still had a working APC gene.

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