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BioGenes Launches Enhanced Generic HCP Assay for Early Stage Biologics Production


9/18/2013 8:33:43 AM

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Berlin, Germany, September 18, 2013 / B3C newswire / - BioGenes GmbH, a global leader in host cell protein (HCP) assay development, today announced that it has launched a new generic HCP assay with enhanced HCP recovery properties. The CHO|360-HCP ELISA is designed to cover the broadest possible spectrum of antigens by integrating four different assay types. An upfront feasibility test will identify the most suitable ELISA kit thus allowing to greatly increasing HCP recovery.

CHO|360-HCP ELISAs employ antibodies of HCPs from different species. By immunizing rabbits and goats with HCPs of a non-transfected CHO cell line combined with a unique approach for antigen and antibody preparation as well as an optimized purification strategy, BioGenes has developed a panel of four different HCP ELISAs that altogether build up the enhanced generic CHO|360-HCP Assay.

Dagmar Schwertner-Knoll, Marketing Director of BioGenes GmbH said: “Our strategy is to offer different ELISA kits for HCP detection. An upfront feasibility test, performed by the customer or by BioGenes as a service, enables the selection of the most suitable kit for a specific process and greatly increases the HCP recovery for most samples.”

For all four assay types the lower limit of detection (LOD) is between 0.5–1 ng/ml and the lower limit of quantification (LOQ) is 2–3 ng/ml with a working range between 2–100 ng/ml. A high specificity for the antigen in all four assays was determined by 2D western blotting with the respective antibodies.

About BioGenes GmbH

BioGenes GmbH specializes in highly sophisticated and customized antibody and immunoassay development and is an experienced and reliable partner for process development improvements in all areas of quality control, diagnostics and drug discovery. BioGenes is certified to meet the international requirements and regularities of quality assurance and animal welfare. The Company maintains long-term relationships with research institutes, universities and biotech and pharmaceutical companies, including eight of the ten largest pharmaceutical companies in the world. The company has been evaluated by a leading global accounting and auditing firm to be one of the leading companies in HCP assay development.

Contact

Dagmar Schwertner-Knoll

Marketing/Sales Director

BioGenes GmbH

+49-30-65762380

dagmar.schwertner@biogenes.de

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