AVEO Pharmaceuticals, Inc. Initiates Phase 1b/2a Clinical Trial of Novel, Triple VEGF Receptor Inhibitor AV-951 in Non-Small Cell Lung Cancer

CAMBRIDGE, Mass.--(BUSINESS WIRE)--AVEO Pharmaceuticals, Inc., a biotechnology company leveraging breakthrough discoveries in cancer biology to discover, develop and commercialize targeted oncology therapies, today announced the initiation of a Phase 1b/2a clinical trial of AV-951 as monotherapy for the treatment of advanced non-small cell lung cancer (NSCLC). This new trial expands on the Company’s broad development program for AV-951, a novel triple VEGF receptor inhibitor being studied in multiple single agent and combination clinical trials across a variety of cancer types including renal cell carcinoma, breast cancer, colorectal cancer and now, lung cancer. The Company launched the Phase 1b portion of this new open-label study at leading cancer institutions in the U.S. to evaluate continuous, escalating daily doses of oral AV-951 over four weeks in approximately 21 patients with recurrent or progressive NSCLC, or who are non-responsive to standard therapy.