AstraZeneca PLC Successfully Reinforces Pipeline With "Open Innovation"

Mene Pangalos is the man tasked with nothing less than firing up the discovery engine of Britain’s second-biggest drug maker after its catastrophic fall off the “patent cliff”. He joined AstraZeneca as head of innovative medicines in 2010, as the company was bracing for patents to expire on a string of its best-selling drugs. The Nineties had been productive for Astra, but the pipeline had dried up. Its research teams were still churning out plenty of “candidate” medicines, but most of them were failing when tested in real patients.

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