BioSpace.com

Biotech and Pharmaceutical
News & Jobs
Search the Site
 
   
Biotechnology and Pharmaceutical Channel Medical Device and Diagnostics Channel Clinical Research Channel BioSpace Collaborative    Job Seekers:  Register | Login          Employers:  Register | Login  

NEWSLETTERS
Free Newsletters
Archive
My Subscriptions

NEWS
News by Subject
News by Disease
News by Date
PLoS
Search News
Post Your News
JoVE

CAREER NETWORK
Job Seeker Login
Most Recent Jobs
Browse Biotech Jobs
Search Jobs
Post Resume
Career Fairs
Career Resources
For Employers

HOTBEDS
Regional News
US & Canada
  Biotech Bay
  Biotech Beach
  Genetown
  Pharm Country
  BioCapital
  BioMidwest
  Bio NC
  BioForest
  Southern Pharm
  BioCanada East
  US Device
Europe
Asia

DIVERSITY

INVESTOR
Market Summary
News
IPOs

PROFILES
Company Profiles

START UPS
Companies
Events

INTELLIGENCE
Research Store

INDUSTRY EVENTS
Biotech Events
Post an Event
RESOURCES
Real Estate
Business Opportunities

 News | News By Subject | News by Disease News By Date | Search News
eNewsletter Signup
Miles
Km80.5

   

Arana Therapeutics Granted Patents in Australia


3/23/2009 12:27:11 PM

Monday, March 23, 2009 Sydney, Australia: Arana Therapeutics Ltd (ASX: AAH) today announced that it has been awarded patents by the Australian Patent Office covering PMX53 and related compounds.

Australian patent, No. 2002336783 covers PMX53 and a range of related compounds as G protein coupled receptor antagonists, including the C5a receptor antagonists, and Australian patent number 2003269609 covers the use of such compounds in osteoarthritis. The patent terms run until 2022 and 2023 respectively. PMX53 and the related family of compounds are small cyclic peptides that have the potential to be used as drugs in a range of inflammatory conditions including age related macular degeneration (AMD) and osteoarthritis.

“The approval of these patents strengthens our PMX portfolio which we are seeking to out-license. We are responding to a number of companies who have expressed interest in evaluating PMX53 and we will continue to progress all discussions with an aim of maximising the value of this asset,” said Steffen Nock, Acting chief executive officer. “PMX53 is a potent molecule with demonstrated activity in various non-ocular disease models. The issuance of these patents provides us with an additional tool in potential negotiations,” he added.

Background

PMX53 and related compounds

Complement is a key component of the inflammatory cascade and is implicated in a number of human inflammatory diseases. PMX53 and its family of related compounds are inhibitors of the human C5a ‘complement’ factor receptor. PMX53 is the compound that Arana has been developing for clinical use in AMD and is testing for its potential use in osteoarthritis. PMX53 a cyclic hexapeptide compound and behaves as an insurmountable antagonist with nanomolar affinity for the human C5a receptor.

About Arana Therapeutics:

Arana Therapeutics (ASX: AAH) is a biopharmaceutical company focused on developing next generation antibody based drugs that will improve the lives of patients with inflammatory diseases and cancer.

Arana Therapeutics’ innovative engineering technologies provide the basis for developing its next generation antibody candidates. Arana Therapeutics has the financial strength and management expertise to develop its product pipeline.

Arana has a significant track record of commercialising its technologies and has collaborations with GlaxoSmithKline (GSK), CSL, Kyowa Hakko Kirin (KHK), and licensing arrangements with Centocor (J&J) and Abbott Laboratories.

For further information: www.arana.com

Read at BioSpace.com

   

ADD TO DEL.ICIO.US    ADD TO DIGG    ADD TO FURL    ADD TO STUMBLEUPON    ADD TO TECHNORATI FAVORITES