AnaSpec, Inc. Highlights Beta-Amyloid (1-40) Peptides

Fremont CA – June 14, 2012 -- ß-Amyloid (1-40) together with ß-Amyloid (1-42) are two major C-terminal variants of the Aß protein constituting the majority of Aßs, with Ab (1-42) being more neurotoxic. These undergo post-secretory aggregation and deposition in the Alzheimer’s diseased brain.1-5

AnaSpec, EGT Group is pleased to be a provider of a large collection of ß-Amyloid (1-40) peptides:

• Native sequences – human and mouse/rat sequences (unless otherwise specified, sequences are human in origin)

• Single or multiple amino acid substitution sequences, e.g. S26C

• Biotin labeled sequences – N or C terminally labeled, with or without linker

• Dye labeled sequences – HiLyte Fluor™ or classic dye labeled

• ClearPoint™ heavy-isotope labeled sequences

• Shorter sequences that end on the 40th amino acid and analog

• HFIP treated ß-Amyloid (1-40)

References:

1. Masters, CL. et al. Proc Natl Acad Sci USA 82, 4245 (1985).

2. Yankner, BA. Neuron 16, 921 (1996).

3. Geula, C. et al. Nat Med 4, 827 (1998).

4. Shin, R. et al. J Neurosci 17, 8187 (1997).

5. Suzuki, N. et.al. Science 264, 1336 (1994).

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AnaSpec, EGT Group

AnaSpec, Eurogentec Group is a leading provider of integrated proteomics and genomics solutionsTM for worldwide life science research. AnaSpec offers expertise in peptides, detection reagents, antibodies, assay kits, amino acids, oligonucleotides, and qPCRs. AnaSpec carries a broad product line of biochemicals and reagents for basic research, high-throughput screening and drug discovery. AnaSpec also provides premier custom services including peptide synthesis, antibody production, assay development, fluorescent dyes, and oligonucleotide synthesis. AnaSpec is certified to ISO 9001:2008.

For more information visit www.anaspec.com