Alfact Innovation Will Present Positive Results for Treatment of AIH- and HBV- Related Acute-on-Chronic Liver Diseases at AASLD
10/24/2013 10:11:35 AM
October 24, 2013 -- Alfact Innovation, a young innovative biotechnology company focused on the discovery
and the development of biopharmaceuticals to provide innovative therapies in hepatology
and oncology disorders, announced positive results from Phase II clinical trial for
treatment of AIH- and HBV- related acute-on-chronic liver diseases.
Alfact Innovation has developed ALF-5755, a recombinant protein of the human protein
HIP/PAP with in vivo therapeutic effect on a fas model of Acute Liver Failure.
Acute Liver Failure – ALF – is a rare condition in which the liver rapidly loses its ability to function,
resulting in coagulopathy and alteration in the mental status of a previously healthy individual.
Despite the improvement in overall survival in the last 20 years due to emergency interventions, ALF
remains a life-threatening disease with about 30% of mortality rate. Hence, ALF remains a high
unmet medical need.
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