Alcon, Inc. to Enter Surgical Glaucoma Market by Acquiring Optonol

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* Acquisition reflects increasing importance of glaucoma surgery to preserve vision
* Entry into glaucoma surgery provides additional near term growth opportunity for Alcon

HUENENBERG, Switzerland--(BUSINESS WIRE)--Alcon (NYSE:ACL) announced today that it has entered into a definitive agreement to acquire Optonol, Ltd., a medical device company that develops, manufactures and markets novel miniature surgical implants used to lower intraocular pressure (IOP) in patients with glaucoma. With this acquisition, Alcon will acquire Optonol’s Ex-PRESS™ Mini Glaucoma Shunt. This agreement will complement Alcon’s pharmaceutical products that lower IOP in patients with glaucoma and ocular hypertension, and will be additive to the company’s growth opportunities.

“This transaction demonstrates Alcon’s strong commitment to providing physicians with comprehensive treatment options for patients with glaucoma, the world’s second leading cause of blindness,” said Robert Warner, Alcon’s vice president of U.S. pharmaceutical products. “This surgical procedure provides incremental surgeon and patient benefits over trabeculectomy, which is currently considered the standard of care in glaucoma surgical therapy.”

The American Medical Association (AMA) assigned the Ex-PRESS™ Mini Glaucoma Shunt to CPT® 0192T effective July 1, 2008 and it is currently reimbursed by Medicare and other payors. The device is also approved and currently marketed in Europe, Canada, Australia and several other countries.

“The acquisition of Optonol is part of our strategy to bolster organic growth with targeted investments in key therapeutic areas that have the potential to contribute in both the near and long term,” said Kevin Buehler, Alcon’s president and chief executive officer. “Because the product is already approved in the United States and other major markets it will begin contributing commercially in 2010.”

The closing of the acquisition is subject to customary closing conditions and the receipt of required regulatory approvals and is expected to occur by the end of the first quarter of 2010.

About Glaucoma

Glaucoma is an eye disease that causes loss of sight by damaging a part of the eye called the optic nerve. When glaucoma damages the optic nerve, subtle loss of vision begins in the peripheral vision and can progress to loss of central vision and blindness. Glaucoma has no signs or symptoms and sufferers usually do not notice the disease until significant vision loss has occurred.

According to the World Health Organization (WHO), the estimated number of persons blinded as a result of open angle glaucoma is 4.5 million, accounting for more than twelve percent of all global blindness.

About Optonol

Optonol, Ltd. is a privately held company located in Neve Ilan, Israel, that manufactures and markets the Ex-PRESS™ Mini Glaucoma Shunt. The

Ex-PRESS™ device reduces intraocular pressure (IOP) by diverting the aqueous humor from the anterior chamber into the subconjunctival space of the eye. The procedure has comparable IOP lowering effectiveness to a trabeculectomy, but it is more predictable, more efficient and associated with less post-operative complications.

About Alcon

Alcon, Inc. is the world’s leading eye care company, with sales of approximately $6.3 billion in 2008. Alcon, which has been dedicated to the ophthalmic industry for 65 years, researches, develops, manufactures and markets pharmaceuticals, surgical equipment and devices, contacts lens solutions and other vision care products that treat diseases, disorders and other conditions of the eye. Alcon operates in 75 countries and sells products in 180 markets. For more information on Alcon, Inc., visit the Company’s web site at www.alcon.com.

Caution Concerning Forward-Looking Statements. This press release may contain forward-looking statements within the meaning of the United States Private Securities Litigation Reform Act of 1995. Any forward-looking statements reflect the views of our management as of the date of this press release with respect to future events and are based on assumptions and subject to risks and uncertainties. Given these uncertainties, you should not place undue reliance on these forward-looking statements. Except to the extent required under the federal securities laws and the rules and regulations promulgated by the Securities and Exchange Commission, we undertake no obligation to publicly update or revise any of these forward-looking statements, whether to reflect new information or future events or circumstances or otherwise.

Contact:

Alcon, Inc. Doug MacHatton, 817-551-8974 doug.machatton@alconlabs.com or Melissa Mota, 817-551-4007 melissa.mota@alconlabs.com www.alcon.com

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