BioSpace.com

Biotech and Pharmaceutical
News & Jobs
Search the Site
 
   
Biotechnology and Pharmaceutical Channel Medical Device and Diagnostics Channel Clinical Research Channel BioSpace Collaborative    Job Seekers:  Register | Login          Employers:  Register | Login  

NEWSLETTERS
Free Newsletters
Archive
My Subscriptions

NEWS
News by Subject
News by Disease
News by Date
PLoS
Search News
Post Your News
JoVE

CAREER NETWORK
Job Seeker Login
Most Recent Jobs
Browse Biotech Jobs
Search Jobs
Post Resume
Career Fairs
Career Resources
For Employers

HOTBEDS
Regional News
US & Canada
  Biotech Bay
  Biotech Beach
  Genetown
  Pharm Country
  BioCapital
  BioMidwest
  Bio NC
  BioForest
  Southern Pharm
  BioCanada East
  US Device
Europe
Asia

DIVERSITY

INVESTOR
Market Summary
News
IPOs

PROFILES
Company Profiles

START UPS
Companies
Events

INTELLIGENCE
Research Store

INDUSTRY EVENTS
Biotech Events
Post an Event
RESOURCES
Real Estate
Business Opportunities

 News | News By Subject | News by Disease News By Date | Search News
eNewsletter Signup
Miles
Km80.5

   

7TM Pharma: A Potential New Treatment For Cancer Supportive Care And Gastrointestinal Diseases


4/23/2010 1:54:45 PM

Hoersholm – April 22, 2010: 7TM Pharma reports promising preclinical data in models of cancer therapy-induced gastrointestinal disease supporting the potential of TM30339, an analogue of a natural human hormone, in cancer supportive care and treating other gastrointestinal diseases.

TM30339 has demonstrated the potential to improve animal survival and mucositis outcome post X-ray irradiation potentially through a crypt survival led mechanism.

Christian E. Elling, Vice President of 7TM Pharma commented: “These preclinical data support that TM30339 may have the potential to treat diseases such as mucositis and inflammatory bowel diseases, while importantly presenting a different pharmacological and mechanistic approach when compared to current drugs and compounds in development. As we already have substantial clinical understanding of the safety and tolerability of TM30339, we intend to investigate the full potential of this compound in these indications”.

About TM30339

TM30339 was discovered and developed by 7TM Pharma. TM30339 is a potent peptide analogue of a natural human hormone from the pancreas, which selectively stimulates the NPY Y4 receptor.

About cancer therapy and gastrointestinal diseases

Most chemotherapy and radiation based cancer treatments destroy a portion of the rapidly dividing epithelial cell lining of the digestive tract resulting in ulceration and inflammation of the oral cavity and the gut, a condition that is known as mucositis. Mucositis is thus a common and often debilitating complication of cancer treatment, which decreases the quality of life of affected patients, may lead to prolonged hospitalization, and may limit the dose and efficacy of the cancer treatment.

The incidence of mucositis varies with different cancer therapies, but may affect 40 – 100 % of subjects treated with certain antineoplastic agents or full body radiation.

About 7TM Pharma

7TM Pharma is a biotech company focusing on the clinical development of drugs with a primary therapeutic focus on obesity, gastrointestinal diseases and with its partner Ortho-McNeil-Janssen Pharmaceuticals (a Johnson and Johnson company) inflammation. 7TM Pharma’s approach is to actively seek licensing partners during early clinical development. Please visit www.7tm.com to see where you can meet us and where we are to present these data.

7TM’s investors include Novo A/S, Alta Partners, LD Pensions, Index Ventures, Scottish Widows Investment Partnership, Sofinnova Capital, SR One, Global Life Science Ventures and GIMV. For more information on 7TM Pharma, please visit www.7tm.com.


Read at BioSpace.com

   

ADD TO DEL.ICIO.US    ADD TO DIGG    ADD TO FURL    ADD TO STUMBLEUPON    ADD TO TECHNORATI FAVORITES