3D Biomatrix Introduces Perfecta3D™ 384-Well Hanging Drop Plates for Three-Dimensional Spheroid Growth and Analysis

Ann Arbor, MI (PRWEB) August 02, 2011 -- 3D Biomatrix is pleased to introduce the Perfecta3D Hanging Drop Plate, a versatile three-dimensional (3D) cell culture device designed to simplify and streamline spheroid formation, culture, and subsequent testing of the 3D cellular constructs. Spheroid cultures grown in Perfecta3D Hanging Drop Plates allow drug discovery researchers to easily mimic tissue metabolic and proliferative gradients, to capture complex cell-matrix and cell-cell interactions, and to monitor cell growth easily and regularly.

“Three-dimensional culture and testing of cells is driven by the need to work with accurate in vitro models that closely mimic living tissues,” said Laura Schrader, CEO of 3D Biomatrix. “3D Biomatrix has developed a versatile, 384-well 3D cell culture plate that makes spheroid culture and analysis as straightforward to perform as conventional two-dimensional (2D) cultures. Perfecta3D Hanging Drop Plates are an efficient way to obtain biological insights that are often lost in 2D platforms, which quickly translates to significant savings for the drug discovery researcher.”

Perfecta3D Hanging Drop Plates facilitate efficient formation of uniform-size spheroids with reduced consumption of media and reagents. The hanging drop size is securely confined by the geometry of the plate. This eliminates spreading, keeps the geometry of the hanging drop consistent, and provides robust and stable culturing conditions. A water reservoir, constructed around the periphery of the culture sites, alleviates the commonly encountered hanging drop evaporation problem. With media easily maintained from the top of the plate, Perfecta3D Hanging Drop Plates are suitable for long-term spheroid culture. In addition, the standardized 384-well plate format is also compatible with high-throughput screening instruments.

Perfecta3D Hanging Drop Plates have been successfully used with a wide variety of cell lines, including human cells (bone marrow endothelial, embryonic kidney, fetal osteoblast and umbilical endothelial) human carcinoma lines (epithelial, prostate, liver, breast anaplastic and adenocarcinoma), murine stem and osteoblastic cell lines among others.

Visit http://www.3dbiomatrix.com for more information and to place your order.

About 3D Biomatrix

3D Biomatrix, LLC is a life sciences company developing and marketing revolutionary solutions for three dimensional (3D) cell cultures. Cells grown on 3D Biomatrix products have been shown to retain a much higher complexity of body response than cells grown in traditional two-dimensional plates and flasks. 3D Biomatrix products benefit life science research and drug discovery applications by providing a faster path to market of new drugs due to improved efficacy and toxicity analysis. 3D Biomatrix technology has been featured on the cover of Analyst, and in Nature Nanotechnology, The Economist, Cosmetics Design - Europe, Pharma Discovery and Development, Nanowerk, ScienceDaily and BiotechDaily publications. For more information, please visit http://www.3dbiomatrix.com.

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