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HighTech Business Decisions Release: High Throughput Screening: Pushing For Higher Quality Leads



10/19/2005 5:09:37 PM

In 2003, HTS laboratories took on more responsibility and became more closely aligned with the project teams, therapeutic areas, and medicinal chemistry departments to increase productivity for drug discovery. Directors from the 51 HTS laboratories participating in the recently published study, High Throughput Screening 2003: Improving Strategies, Technologies, and Productivity, identified 74 drug candidates that originated in their HTS laboratories that are being tested in humans and two are on the market. To increase drug discovery success, 89% of the HTS laboratories in this study now conduct secondary screens as well as primary screens, and 25% are conducting in vitro ADME/Tox screens. Overall, more downstream and upstream screening is being done in HTS laboratories.



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