CHICAGO, March 8 /PRNewswire/ -- A next generation HPLC column for LC/MS applications, ZirChrom(R)-MS, will be featured by ZirChrom Separations, Inc. at the Pittcon 2004 Trade Show in Chicago, IL. The new surface deactivated ZirChrom(R)-MS column offers enhanced retention, unique selectivity, and improved peak shape for basic pharmaceutical compounds compared to other columns currently on the market.
On Tuesday, March 9, 2004 at 4:45pm in Room # S504d of the McCormick Convention Center Dr. Clayton McNeff, CEO, ZirChrom, will present the results of a recently completed column comparison study focusing on ZirChrom(R)-MS in his presentation entitled, "Synthesis of a New Thermally and Chemically Stable Lewis Acid Deactivated Reversed-Phase Zirconia Stationary Phase for LC/MS." Summaries of the column comparison study will be made available at booth #874 during the Pittcon 2004 Trade Show (March 8 - 11).
The following unique features make ZirChrom(R)-MS columns an ideal choice for today's LC/MS method developer:
-- Compatible with volatile, near neutral pH mobile phase buffers.
-- Enhanced retention for basic drugs compared to bonded phase C18
-- Radically different selectivity for basic drugs compared to bonded
phase C18 silica.
-- Improved peak shape and efficiency for basic drugs compared to bonded
phase C18 silica.
-- Allows for simultaneous analysis of basic, acidic and neutral
-- Low column bleed characteristics due to covalent bonding chemistry.
Dr. Bingwen Yan, Senior Scientist, ZirChrom, said, "The results of the column comparison study are further proof that ZirChrom(R)-MS represents a major advance for reversed-phase HPLC. This new column is ideal for the separation of basic compounds under conventional LC/MS compatible operating conditions. Our research demonstrates that the ZirChrom(R)-MS column has very different chromatographic selectivity, especially for basic pharmaceuticals, that distinguish it from traditional bonded C18 and other more novel silica phases."
About ZirChrom Separations
ZirChrom Separations, Inc. is a company formed in 1995 and located in Anoka, Minnesota. ZirChrom manufactures a full line of zirconia-based high performance chromatographic materials for analysis and purification by high performance liquid chromatography (HPLC).
ZirChrom Separations, Inc.