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Genomatica, Inc. Enters Into Multi-Year Collaboration With DSM, A Leading Chemical Company Of The Netherlands

10/19/2005 5:13:09 PM

SAN DIEGO, April 19 /PRNewswire/ -- Genomatica, Inc., a leading computational systems biology company focused on metabolism research, announced today it has entered into a collaboration and license agreement with DSM, a global supplier of ingredients based on fermentation and enzyme technology to the chemical, pharmaceutical and food industries. Under the collaboration, DSM will license SimPheny(TM), Genomatica's modeling and simulation platform to help guide DSM's research efforts for a broad application range, including strain engineering and process development. In addition, Genomatica and DSM will jointly develop and implement within SimPheny a metabolic model of a proprietary production organism key to DSM. Financial details of the agreement were not disclosed, but include license fees and milestone payments.

"We are excited to be working with DSM, one of the largest chemical and biotechnology companies in Europe," Commented Christophe H. Schilling, Ph.D., President and Chief Scientific Officer at Genomatica. "DSM has recognized the power of model-driven metabolic research for bioprocessing and pharmaceutical research and we are delighted that DSM has selected SimPheny as a key component for a robust Bio-IT infrastructure within the DSM global organization."

"Genomatica's SimPheny(TM) platform will be an important element in DSM's newly designed Genomics and Bio-IT infrastructure", says Dr. Bob Poldermans, Research Director at DSM Food Specialties. "We see a lot of opportunities for improving our biotechnological processes through an integrated use of the genomics disciplines. The powerful modeling capabilities of SimPheny(TM) will prove to be of great help in reaching our goals."

In addition to licensing its technology to DSM, Genomatica announced in January it had entered into a license agreement with Kyowa Hakko, a major Japanese biotechnology company.

About Genomatica

Genomatica is a leading innovator of biological modeling and simulation technologies transforming biological research and the way microorganisms are engineered and drugs are discovered. Using validated technology, Genomatica delivers industry-leading solutions for the modeling and simulation of metabolism. These solutions drive a powerful new paradigm, called Model-Driven Metabolic Research, wherein computer models are used to accelerate biological research and discovery across the life sciences. Genomatica is advancing the frontiers of biological discovery and the development of innovative products in medical and industrial biotechnology, while streamlining existing product development and enhancing the overall business efficiency of its clients. Genomatica has developed SimPheny, a client-server application that enables the development of predictive computer models of organisms, from bacteria to humans. With cellular metabolism at its core, SimPheny can build virtual cells from their basic molecular components, and can simulate the activity of the cell's complete reaction network. Genomatica is currently pursuing commercial relationships with major bioprocessing, pharmaceutical and biotechnology companies seeking to leverage the power of model-driven systems biology for rapid biological discovery. For more information, please visit us on our website at

Genomatica, Inc.

CONTACT: Christophe H. Schilling, Ph.D., President & Chief ScientificOfficer, or Thomas A. Reed, Vice President, Finance & Corporate Development,or Amy L. Buono, Media Relations, all of Genomatica, Inc., +1-858-824-1771

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