BioSpace.com

Biotech and Pharmaceutical
News & Jobs
Search the Site
 
   
Biotechnology and Pharmaceutical Channel Medical Device and Diagnostics Channel Clinical Research Channel BioSpace Collaborative    Job Seekers:  Register | Login          Employers:  Register | Login  

NEWSLETTERS
Free Newsletters
Archive
My Subscriptions

NEWS
News by Subject
News by Disease
News by Date
PLoS
Search News
Post Your News
JoVE

CAREER NETWORK
Job Seeker Login
Most Recent Jobs
Browse Biotech Jobs
Search Jobs
Post Resume
Career Fairs
Career Resources
For Employers

HOTBEDS
Regional News
US & Canada
  Biotech Bay
  Biotech Beach
  Genetown
  Pharm Country
  BioCapital
  BioMidwest
  Bio NC
  BioForest
  Southern Pharm
  BioCanada East
  US Device
Europe
Asia

DIVERSITY

INVESTOR
Market Summary
News
IPOs

PROFILES
Company Profiles

START UPS
Companies
Events

INTELLIGENCE
Research Store

INDUSTRY EVENTS
Biotech Events
Post an Event
RESOURCES
Real Estate
Business Opportunities

 News | News By Subject | News by Disease News By Date | Search News
eNewsletter Signup
Miles
Km80.5

   

Afferent Corporation Announces Research Results; Company's Neurotechnology Improves Foot Sensation In People With Diabetes


10/19/2005 5:09:31 PM

PROVIDENCE, R.I.--(BUSINESS WIRE)--Dec. 16, 2003--Afferent Corporation today announced publication of research results pertaining to use of the Company's technology in treating nerve dysfunction stemming from diabetes. Performed in collaboration with Aristidis Veves, M.D., D.Sc., Director of the Joslin-Beth Israel Deaconess Foot Center, Boston, MA, the study showed that prototypes of the Company's non-invasive neural stimulation devices improved sensitivity to touch on the feet of diabetic subjects with reduced nerve function. Appearing in the December issue of the leading clinical journal Diabetes Care, the findings have implications in lowering the incidence of dangerous foot ulcers in these individuals. For millions of diabetic patients with peripheral neuropathy, the sense of touch in the extremities can deteriorate over time. This loss of sensitivity, combined with reduced blood circulation in the skin, contributes to the development of foot ulcers. These debilitating skin wounds can be extremely difficult to heal, and lead to more than 80,000 lower extremity amputations each year in the U.S. Costs to treat diabetes-related foot problems exceed $4 billion annually.

In this pilot clinical study, supported by a research grant from the National Institutes of Health, 20 subjects with moderate-to-severe peripheral neuropathy received subsensory vibratory mechanical stimulation delivered to the sole of the foot in a series of trials. Changes in touch sensitivity were measured using standard neurological exams: Semmes-Weinstein monofilaments and a vibration perception threshold test. The presence of the stimulation significantly improved subjects' ability to detect small pressures and vibrations, on average by 20% for the group.

Commenting on these findings, Dr. Veves stated, "Peripheral neuropathy and the health problems that stem directly from it represent some of the most dangerous aspects of diabetes. Although further clinical testing is required, this result is a significant advance toward what may prove to be an important new therapy for reducing the occurrence of foot ulceration in these patients."

Jason Harry, Ph.D., President and CEO of Afferent Corporation, said, "We believe this is an important milestone in validating the potential of this technology to treat those suffering from diabetic neuropathy. As our development efforts continue in this and other clinical areas, we will create new therapeutic options for patients with sensory dysfunction." Afferent's neurotechnology originated in landmark research performed at Boston University's Center for Biodynamics.

About Afferent Corporation

Afferent Corporation is pioneering the development of a new class of medical devices to treat chronic neurological dysfunction. Its lead technology enhances the function of mechanoreceptor cells involved in sensory perception as a means of restoring brain function following stroke, addressing complications resulting from diabetic neuropathy, and improving elderly balance. Afferent's development efforts are being pursued in collaboration with leading biomedical and clinical researchers throughout the United States and Canada. Building on this technology platform, Afferent aims to establish a leadership position in the emerging field of neurotherapeutic devices.

Contact:

Cutler Communications Andy Cutler, 401/751-2486 (office) 401/743-7842 (cell) andy@cutlerpr.com

Source: Afferent Corporation



Read at BioSpace.com

   
Diabetes

ADD TO DEL.ICIO.US    ADD TO DIGG    ADD TO FURL    ADD TO STUMBLEUPON    ADD TO TECHNORATI FAVORITES